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ECHO、DCG及MSCT冠脉成像在无症状心肌缺血临床诊断中的应用

作者:代聚平 罗 静 闫 丽 吴小星

所属单位:南阳医专一附属医院心血管内科 (河南 南阳 473000)

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摘要

目的 分析超声心动图(ECHO)、 动态心电图(DCG)、多排螺旋电子计算机断层扫描(MDCT)冠脉成像在无症状心肌缺血(SMI)临床诊断中的应用效果。方法 回顾性分析我院84例疑似SMI患者临床资料,所有患者均行ECHO、DCG、MSCT冠脉成像及冠状动脉造影(CAG)检查,并以CAG 诊断结果作为金标准,比较ECHO、DCG、 MSCT冠脉成像对SMI的诊断价值。结果 84 例疑似SMI患者中,经CAG确诊SMI有69例 (82.14%)。MSCT冠脉成像诊断SMI准确77 例(91.67%),漏诊5例(7.25%),误诊2例 (13.33%),Kappa值为0.737;DCG诊断SMI 准确73例(86.90%),漏诊8例(11.59%), 误诊3例(20.00%),Kappa值为0.605; ECHO诊断SMI准确66例(78.57%),漏诊14 例(20.29%),误诊4例(26.67%),Kappa值 为0.421。3种检查方法Kappa值以MSCT冠 脉成像最高;3种检查方法特异度、阳性 预测值、阴性预测值比较,差异无统计学 意义(P>0.05);MSCT冠脉成像灵敏度、 准确率均高于ECHO(P<0.05);但MSCT冠 脉成像与DCG灵敏度、准确率比较,差异 无统计学意义(P>0.05);ECHO与DCG灵敏 度、准确率比较,差异亦无统计学意义 (P>0.05)。结论 ECHO、DCG及MSCT冠脉 成像在SMI临床诊断中具有一定作用,但 MSCT冠脉成像准确性更高,临床实用价值 较高。

Objective To analyze the application effects of echocardiography (ECHO),  dynamic electrocardiogram (DCG) and multi-slice spiral computed tomography (MDCT) coronary angiography in the clinical diagnosis of silent myocardial ischemia (SMI). Methods The clinical data of 84 patients suspected as SMI were analyzed retrospectively. All patients  were given ECHO, DCG, MSCT coronary angiography and coronary arteriography  (CAG). The results of CAG diagnosis were used as the gold standard to compare the  diagnostic value of ECHO, DCG and MSCT coronary angiography for SMI. Results Among 84 patients suspected as SMI, 69 cases (82.14%) were diagnosed by CAG. MSCT coronary angiography in the diagnosis of SMI showed there were 77 cases (91.67%) of  accurate diagnosis, 5 cases (7.25%) of missed diagnosis and 2 cases (13.33%) of misdiagnosis,  and the Kappa value was 0.737. DCG in the diagnosis of SMI showed there were 73 cases  (86.90%) of accurate diagnosis, 8 cases ( 11.59%) of missed diagnosis and 3 cases (20.00%)  of misdiagnosis, and the Kappa value was 0.605. ECHO in the diagnosis of SMI showed  there were 66 cases (78.57%) of accurate diagnosis, 14 cases (20.29%) of missed diagnosis  and 4 cases (26.67%) of misdiagnosis, and the Kappa value was 0.421. The Kappa value of  three examination method was the highest in MSCT coronary angiography. There were  no significant differences in the specificity, positive predictive value and negative predictive  value among the three examination methods (P>0.05). The sensitivity and accuracy of  MSCT coronary angiography were higher than those of ECHO (P<0.05). However, there  were no significant differences in the sensitivity and accuracy between MSCT coronary  angiography and DCG (P>0.05). There were no significant differences in the sensitivity  and accuracy between ECHO and DCG (P>0.05). Conclusion ECHO, DCG and MSCT  coronary angiography have a certain role in the clinical diagnosis of SMI, but MSCT  coronary angiography has higher accuracy and higher clinical value.

【关键词】无症状心肌缺血;ECHO、DCG、MDCT、冠状动脉成像

【中图分类号】R54;R81

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2019.09.022

前言

  无症状心肌缺血(Silent myocardial ischemia, SMI)是指解剖学 上存在冠状动脉病变,但缺乏心肌缺血临床症状的一类疾病,好发于中老年人群,并广泛隐匿于冠心病患者中,亦能进展为心肌梗死或恶 性心律失常而猝死[1]。因此,及时确诊SMI,并尽早行临床干预,对我 国中老年人群生命健康非常重要。目前,诊断SMI的金标准仍为冠状动 脉造影(CAG),但该检查手段有创、临床应用受到一定限制[2]。故探寻 其他无创且有效的检查方法有其必要性。超声心动图(ECHO)、动态心 电图(DCG)、多排螺旋电子计算机断层扫描(MDCT)冠脉成像均为临床评 估心肌缺血的常用方法,具有无创、高效等优点[3]。基于此,本研究回 顾性分析我院84例疑似SMI患者临床资料,以评估ECHO、DCG、MDCT冠 脉成像在诊断SMI中的应用价值,现报告如下。