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磷酸奥司他韦治疗流行性感冒的临床疗效

作者:谭于飞 麻恒翔

所属单位:河南省驻马店市中心医院呼吸一科 (河南 驻马店 463000)

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摘要

目的 探讨磷酸奥司他韦对流行性感冒的临床治疗效果。方法 选择我院2015年5月至2017年1月收治的130例流行性 感冒患者为研究对象,随机分为对照组65例,观察组65例,对照组使用常规方案治疗,观察组在常规方案治疗基础 上加磷酸奥司他韦治疗,对两组患者临床治疗效果进行分析。结果 观察组治疗总有效率(92.31%)明显高于对照组 (73.85%),观察组发热缓解时间、症状缓解时间、流感缓解时间较对照组短,差异存在统计学意义(P<0.05)。结 论 流行性感冒采取磷酸奥司他韦治疗的效果满意,可快速缓解症状,利于减轻患者痛苦,值得推广。

Objective To investigate the clinical effect of oseltamivir phosphate on flu. Methods From May 2015 to Jan. 2017, a total of 130 patients with flu in our hospital were taken as the research objects, and they were randomly divided into control group (65 cases) and observation group (65 cases). Both groups were given conventional therapy, besides, the observation group was given additional oseltamivir phosphate. After treatment, the curative effects in the two groups were compared and analyzed. Results The total effective rate in observation group was 92.31% which was significantly higher than that in the control group of 73.85%, and their difference was statistically significant (P<0.05), after treatment, the fever remission time, symptom relief time and flu release time in the observation group were all significantly shorter than those in the control group (P<0.05). Conclusion Oseltamivir phosphate which has good effect for flu, can quickly relieve symptoms and alleviate the suffering of patients. Thus, it is worthy of promotion.

【关键词】流行性感冒;磷酸奥司他韦;疗效

【中图分类号】R373.1+3

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2018.01.029

前言

流行性感冒是一种常见疾病,其具有发病率高, 传染性强等特点。其病原学不同,可分为丙型、乙型 及甲型,临床对流行性感冒进行治疗的相关药物较 多,但是因见效慢,或者疗效不满意,不良反应发生 率较多等因素,难以被患者所接受[1]。选择一种见效 快,能显著进行病情控制的药物进行治疗,是临床研 究的关键。本组研究对流行性感冒患者实施磷酸奥司 他韦治疗,现进行如下报道。