目的 探讨分析冷冻诊断和常规石蜡诊断用于甲状腺疾病的对比。方法 选择我院2014年10月份到2015年10月份收治 的甲状腺疾病患者，进行冷冻切片和手术后常规石蜡切片检查的1000例做为研究对象。患者手术后病理组织分别 进行冷冻切片检验和常规石蜡切片检验，对比病理结果。结果 1000例患者中，良性占672例，占总病例67.2%；桥 本甲状腺炎55例，占良性患者8.18%；亚急性甲状腺炎5例，占良性患者0.74%、结节状甲状腺肿517例，占良性患 者的76.93%、滤泡性腺瘤79例，占良性患者11.76%、GRVAES病6例，占良性患者0.89%。恶性肿瘤328例，占总病例 32.8%；髓样癌11例，占恶性患者33.54%；滤泡癌7例，占恶性患者2.13%；乳头状癌310例，占恶性患者94.51；完 全符合300例，占91.46%；基本符合5例，占1.52%；误诊20例，占6.1%；延迟3例，占0.91%。结论 冷冻切片的检查 结果可以对患者的病变情况做出准确的判断，是一种快捷、操作简单的检查方法。甲状腺疾病的冷冻切片的诊断应 不断总结临床经验，提高取材以及制片技术，阅片师应具备多年经验，以提高诊断的准确率为目的，降低误诊率。

Objective To explore the comparison between cryodiagnosis and conventional paraffin diagnosis for thyroid diseases. Methods 1000 cases of thyroid disease treated by our hospital from October 2014 to October 2015 were selected as the study subjects. The pathological tissue of the patients after the operation was tested with the frozen section and conventional paraffin section,and the pathological results were compared. Results Of the 1000 patients, 672 were benign, accounting for 67.2%of the total cases. The 55 cases of hashimoto thyroiditis,accounting for 8.18% of the benign patients. Subacute thyroiditis in 5 cases, 0.74%of the patients with benign, 517 cases of nodular goiter,accounting for 76.93% of the patients with benign follicular adenoma,79 cases,11.76%of the patients with benign,GRVAES disease 6 cases, 0.89%of the patients with benign.328 cases of malignant tumor, which accounted for 32.8% of the total cases. 11 cases of medullary carcinoma and 33.54% of malignant patients. 7 cases of follicular cancer and 2.13% of malignant patients. There were 310 cases of papillary carcinoma,and 94.51 were malignant. Total compliance with 300, accounting for 91.46%. Basic compliance with 5 cases, accounting for 1.52%. Misdiagnosis of 20 cases,accounting for 6.1%. Delay in 3 cases, 0.91%. Conclusion The examination results of the frozen section can make accurate judgment of the patient's pathological condition, and it is a quick and easy way to check.Frozen sections of diagnosis of thyroid disease should summarize the clinical experience,constantly improve the materials and production technology, teacher should have many years experience in reading,in order to improve the diagnostic accuracy for the purpose, to reduce the misdiagnosis rate.