目的 探讨尿毒症脑病的MRI表现特征，以提高对本病的影像学检查的认识。方法 回顾性分析2011年6月-2016年6月 经临床证实的25例尿毒症脑病患者的MRI检查资料，分析其MRI特点。结果 5例表现为豆状核对称性信号改变，17例 表现为额、顶、枕叶多发局部病灶，3例广泛脑皮层及皮层下异常信号，22例伴有脑萎缩。结论 尿毒症脑病MRI表 现具有一定特征性，可显示中枢神经系统受损范围及程度，评价疗效，已成为评估尿毒症脑病的首选影像检查。

Objective To discuss the MRI characteristics of uremic encephalopathy and improve the understanding. Methods From June 2011 to June 2016, a total of 25 cases with uremic encephalopathy proven by clinically were selected in this study, and their MRI findings were analyzed. Results 5 cases showed the symmetrical signal features in nucleus lenticular, and 17 cases showed the signal features in frontal, parietal and occipital lobe, 3 cases showed the signal features in cortex and subcortex. 22 cases showed brain atrophy. Conclusion Uremic encephalopathy has some specific MRI features, can show the extent and scope of the central nervous system damage, and evaluate the curative effect. MRI has become the first choice imaging examination for the assessment of uremic encephalopathy.