摘要
目的 研究分析拉莫三嗪与丙戊酸联合治疗癫痫患者的临床效果。方法 选取2015年6月至2017年2月期间在本院接 受诊治的98例癫痫患者,以随机的方式将患者分成研究组与对照组,各为49例;研究组治疗中实施拉莫三嗪与丙 戊酸联合治疗,对照组治疗中单纯应用丙戊酸治疗,观察分析两组入选患者的治疗效果。结果 研究组治疗总疗效 (95.92%)高于对照组(79.59%),研究组总不良反应发生率(6.12%)低于对照组(22.45%),P<0.05。结论 癫痫患者 的治疗中实施拉莫三嗪与丙戊酸联合治疗,具有良好的临床效果。
Objective To study and analyze the clinical effects of lamotrigine combined with acrylic acid in treatment of patients with epilepsy. Methods From June 2015 to February 2017, 98 cases of patients with epilepsy received diagnosis and treatment in our hospital were selected in this study, which were divided into the study group and the control group by the random way with 49 cases in each group. The study group were implemented the lamotrigine combined with valproate treatment, while the control group were treated with valproic acid only. Then, the clinical effect of two groups of patients were observed and analyzed. Results All the patients were treated, and the clinical effect between the evaluation and analysis group showed that the study group was significantly higher than the control group (95.92% vs.79.59%, P<0.05). And the adverse reactions of the patients were observed and compared, the study group were significantly decreased than that in the control group (6.12% vs. 22.45%, P<0.05). Conclusion The implementation of lamotrigine combined with valproate therapy for patients with epilepsy, which it have good clinical effect.
【关键词】癫痫;拉莫三嗪;丙戊酸;临床效果
【中图分类号】R453
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.01.006
前言
癫痫在临床上比较常见,又被称为羊癫风或者羊 角风,为一种脑部慢性疾病。近年来,由于人们生活 方式、社会环境不断改变及生活、工作压力不断增大 等多种因素的影响下,致使癫痫的疾病发生率呈现为 不断上升的趋势[1],严重影响了患者的身体健康及生 活质量等。因此,寻求一种有效性及安全性均比较高 的癫痫治疗方法具有重要的意义,本研究中就对拉莫 三嗪与丙戊酸联合治疗癫痫患者的临床效果进行评价 分析,报道具体如下。
罕少疾病杂志
第25卷, 第 1 期
2019年11月
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