目的 研究分析呼吸困难B型利钠肽测定值在临床中的应用价值。方法 本次研究选取我院2015年2月-2016年2月间 收治呼吸困难患者110例，将患者根据疾病病情进行分组，肺源性呼吸困难患者设为观察组，心源性呼吸困难患者 设为对照组，其中对照组患者59例，参考美国纽约心脏病学会心功能分级标准，II级患者25例，III级患者21例， IV级患者3例；观察组患者51例；对两组患者的静脉血进行采集，并应用电化学发光分析法检测血浆中的利钠肽含 量，应用彩色多普勒超声诊断系统检测患者左室射血分数和左心室舒张末内经。结果 对照组患者的左室射血分数 及BNP水平均高于观察组患者，左心室舒张末内径低于对照组患者，组间存在统计学差异（P<0.05）。在对照组不 同心功能分级患者中，对着心功能的增加，左心室舒张末内径不断增加，左室射血分数不断减少，血清中BNP含量 不断增加。结论 对于呼吸困难的患者应用B型利钠肽含量测定，可诊断患者疾病的严重程度，根据BNP含量可确定 患者呼吸困难的原因，积极对症治疗，改善患者呼吸困难症状，有利于患者预后。

Objective To investigate the application value of B-type natriuretic peptide in patients with dyspnea. Methods 110 cases with dyspnea in our hospital from February 2015 to February 2016 were selected and divided into two groups. Patients with pulmonary dyspnea were seen as observation group. Patient with cardiac dyspnea were seen as control group. There were 59 cases in control group. According to ACC Heart Function Classification Standard, there were 25 cases with class II, 21 cases with class III, 3 cases with class IV, there were 51 cases in observation group; collect the venous blood of the two groups, using ECL to detect the natriuretic peptide content in plasma, using color doppler sonography diagnosing to detect the left ventricular ejection fraction and left ventricular end-diastolic diameter. Results Left ventricular ejection fraction and BNP level of control group were higher than observation group, left ventricular end-diastolic diameter of observation group was lower than control group, the difference was statistic significant(P<0.05). In patients with different cardiac functional grading in control group, with the increasing of cardiac function, left ventricular end diastolic diameter was increased and left ventricular ejection fraction was declined, BNP in serum was increased. Conclusion For patient with dyspnea, measurement of B-type natriuretic peptide content can be used to diagnose severity of illness. BNP content can be used to confirm the reasons of dyspnea. Positive expectant treatment can improve dyspnea and is conducive to patients ' prognosis.