目的 探讨肥胖对支气管哮喘非急性发作期患者肺功能的影响。方法 选取2015年6月至2016年2月期间我院门诊就诊 的支气管哮喘非急性发作期患者120例为研究对象，依据体质指数(BMI)分为肥胖组（BMI＞25kg/m2 ）（n=40）和非 肥胖组（≤25kg/m2 ）（n=60），统计两组近6个月内症状、用药情况等，采用肺功能仪检测两组肺功能指标，包括 用力肺活量（FVC）与其占预计值百分比（FVC% pred）、第1s用力呼气容积（FEV1）与其占预计值百分比（FEV 1% pred）及FEV1/FVC。结果 肥胖组近6个月内哮喘天数、咳嗽天数显著较对照组多，口服激素或吸人激素总量显著较 对照组高（P＜0.01）。肥胖组FVC% pred、FEV 1% pred、FEV1/FVC均明显低于非肥胖组（P＜0.02）。结论 肥胖 与正常支气管哮喘非急性发作期患者相比临床哮喘、咳嗽症状更严重，用药量更大，且肺功能明显较差。

Objective To study the effect of obesity on pulmonary function in patients with bronchial asthma in non-acute episode. Methods From Jun. 2015 to Feb. 2016, a total of 120 patients with bronchial asthma in non-acute episode in our hospital were taken as the clinical research objects, and they were divided into obesity group(BMI>25kg/m2 )(n=40) and non-obesity group(≤25kg/m2 )(n=60) according to body mass index (BMI). In the past 6 months, the symptoms and drug use in the two groups were observed and compared, pulmonary function indexes including forced vital capacity(FVC), forced vital capacity percentage of predicted value(FVC% pred), forced expiratory volume in 1s (FEV1), forced expiratory volume in 1s percentage of predicted value(FEV 1% pred) and FEV1/FVCin the two groups were detected by pulmonary function instrument. Results In the past 6 months, the asthma and cough time in the obesity group was obviously less than that in the control group(P<0.01), the using dosage of hormone in the obesity group was obviously higher than that in the control group(P<0.01), the FVC% pred, FEV 1% pred and FEV1/FVC in the obesity group were all significantly lower than those in the non-obesity group(P<0.02). Conclusion Compared with non-obese patients, obese patients with bronchial asthma in non-acute episode has the following characteristics: more serious asthma and cough symptoms, more using dosage of drugs and obviously poorer pulmonary function.