目的 比较软骨母细胞瘤的CT及 MRI影像表现。方法 纳入我院2011年1 月-2015年12月期间共收集36例软骨母细 胞瘤患者进行研究，均行CT及MRI检查， 比较二者对软骨母细胞瘤临床诊断的价 值。结果 CT表现以病灶边缘硬化、病灶 内钙化、骨膜反应、软组织肿胀、邻近 关节腔积液为主，增强扫描后病灶内均 示轻度到中度强化，CT值增高8-34HU。 MRI示病灶多为卵圆形或类圆形囊状骨质 破坏区、边界清晰，T1WI低信号、T2WI 高低混杂信号，特殊征象包括片状、斑 点状低信号钙化或骨嵴、病灶边缘低信 号硬化带、T2WI病灶周围骨髓腔见长T2 水肿信号。两种检查方法对膨胀性病 变、窗格样改变、骺板或骺线穿越等征 象的检出率无统计学意义(P﹥0.05)；CT 对边界清晰伴边缘硬化、病灶内钙化检 出率分别为61.1%、66.7%，高于MRI的 36.1%、41.7%，对骨髓水肿检出率仅为 2.8%，低于MRI的27.8%，差异均有统计 学意义(P﹤0.05)。结论 CT及MRI诊断软骨 母细胞瘤各有优劣，CT对病灶边缘硬化 及病灶内钙化的显示更佳，对骨髓水肿 显示则较弱，临床诊断时还需与骨巨细 胞瘤、软骨肉瘤、内生软骨瘤等进行鉴 别。

Objective To compare the imaging findings of CT and MRI in chondroblastoma. Methods A total of 36 cases of patients with chondroblastoma who were collected from our hospital between January 2011 and December 2015 were included in the study. CT and MRI examination were performed. The value of the two in clinical diagnosis of chondroblastoma was compared. Results Main CT findings were lesion edge sclerosis, calcification in lesions, periosteum reaction, soft tissue swelling and adjacent joint effusion. After enhanced scan, the lesions showed mild to moderate enhancement. CT value increased 8-34HU. MRI showed that the lesion were orbicular-ovate or quasi-circular cystic bony destruction, with clear boundaries. T1WI showed low signal while T2WI showed high and low hybrid signal. Special findings included flake, speckled low signal calcification or bone crest, low signal sclerosis area on the edges of lesions. T2WI bone marrow cavity around the lesion showed T2 edema signal. There were no significant differences in detection rates of the two examination methods in signs such as expansile lesions, pane-like changes and the epiphyseal plate or epiphyseal line crossing etc. (P>0.05); The detection rates of CT for clear boundary with marginal sclerosis and calcification within the lesions (61.1%, 66.7%) were higher than those of MRI (36.1%, 41.7%) while the detection rate for bone marrow edema (2.8%) was lower than that of MRI (27.8%) (P<0.05). Conclusions CT and MRI in the diagnosis of chondroblastoma have their own advantages and disadvantages. CT can better show marginal sclerosis and calcification within the lesions while is poorer in displaying bone marrow edema. In clinical diagnosis, it needs to be identified from bone giant cell tumor, chondrosarcoma and chondroma etc.