目的研究烟雾病的多层螺旋CT 影像诊断及保守干预前后脑血流变化。方 法 选择我院2011年1月-2015年5月期间 所收治32例烟雾病患者进行研究，均于保 守干预前后分别进行CT检查。观察患者CT 影像学表现，包括容积再现(VR)、大密度 投影(MIP)、(最大密度投影(MIP))曲面重 建(CPR)及多平面重建(MPR)。比较保守干 预前后脑血流变化情况，包括脑血流量 (CBF)、对侧脑血流量(rCBF)、脑血容量 (CBV)、对侧脑血容量(rCBV)、达峰时间 (TTP)、对侧达峰时间(rTTP)。结果 治疗 前后rCBF、CBV、rCBV、rTTP的差异P＞ 0.05，CBF治疗后高于治疗前、TTP为治疗 后低于治疗前，差异均有统计学意义(P ＜0.05)。结论 多层螺旋CT灌注成像在烟 雾病中的应用利于影像学表现明显，利于 确诊，且为无创、快捷检查手段，可通过 对患者脑血流变化的观察明确治疗效果， 判断预后，经济适用，值得应用。

Objective To study multi-slice spiral CT imaging diagnosis of moyamoya disease and the changes of cerebral blood flow before and after conservative intervention. Methods 32 patients with moyamoya disease treated in our hospital from January 2011 to May 2015 were studied. All of them underwent CT examination before and after conservative intervention. CT imaging features were observed, including volume rendering (VR), maximum intensity projection (MIP), curve planar reformation (CPR) and multi planar reconstruction (MPR). The changes of cerebral blood flow before and after the conservative intervention were compared, including cerebral blood flow (CBF), regional cerebral blood flow (rCBF), cerebral blood volume (CBV), contralateral cerebral blood volume (rCBV), time to peak (TTP) and contralateral time to peak (rTTP). Results There were no statistically significant differences in rCBF, CBV, rCBV and rTTP before and after the treatment (P>0.05). CBF after the treatment was higher than that before the treatment while TTP was lower than that before the treatment (P<0.05). Conclusion The application of multi-slice spiral CT perfusion imaging in moyamoya disease is beneficial to clearly show the imaging features and make a definite diagnosis. It is a non-invasive and efficient examination way. Through observing the changes of cerebral blood flow in patients, the curative effect can be determined and the prognosis can be judged. It is affordable and worthy of application.