目的 探讨不同部位中枢神经细 胞瘤的MRI表现及病理特点。方法 对经 病理证实的12例发生在不同部位的中枢 神经细胞瘤MRI资料及病理资料进行回顾 性分析。结果 9例位于侧脑室，1例位于 中脑，2例位于丘脑。12例CNC中，MRI均 表现为T1WI、T2WI混杂信号，其内可见 不同程度的大小不等囊变区，部分可见 “索条征”、出血及钙化等征象，边界 清晰，增强实性部分明显强纤维性基质 形成的无核岛区。免疫组化 Syn 和 NeuN 高表达。结论 侧脑室为中枢神经细胞瘤 的好发部位，结合肿瘤容易囊变、“索 条征”及发病年龄特点，术前多能够做 出正确诊断；脑室外发生较少且MRI表现 缺乏特异性，术前诊断困难。免疫标记 Syn 和 NeuN 在 CNC 的诊断与鉴别诊断 中起到重要作用。

Obsjective To investigate the imaging characters on MR and pathological feature of central neurocytoma. Methods Imaging findings and pathological features of 12 patients with histopathological diagnosis of CNC were evaluated retrospectively. Results 9 cases were located in the lateral ventricle close to Monro Foramina, one was in the mesencephalon and two in the thalamus.The mass could appear various mixed singnals on T1WI and T2WI with well-defined edge. Cystolization, hemorrhage, calcification and "cords sign"could be seen. After contrast administration, the solid parts of the mass were significant enhanced. CNC were composed of uniform small round cell sheet arranged and characterized by pseudorosette and nucleus-free area formed of dense flbrillar matrix. Syn and NeuN were overexpressed in CNC. Conclusion CNC that located in lateral ventricle with "cords sign" and Cyst in young adults could be easy diagnosed. But extraventricular CNC that lacked identifiable imaging characters could be diagnosed with the help of immunohistochemical analysis of Syn and NeuN.