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双源CT双能量成像在肺动脉栓塞诊断中的应用

作者:彭可雨 阮 兵 梁汉欢 张 洪 梁 艳

所属单位:广东省高州市人民医院放射科CT室(广东 高州 525200)

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摘要

目的 探讨双源CT双能量成像在 肺动脉栓塞诊断中的应用价值。方法 收 集在我院使用双源CT双能量肺动脉成像检 查的26例临床资料进行分析,探讨双源CT 双能量肺动脉成像(DEPI)在肺动脉栓塞中 的应用价值。结果 在肺叶基础上,DEPI 与CTPA检出血管栓塞的符合率为96.30%; 在肺段的基础上,DEPI与CTPA检出血管 栓塞的符合率为90.57%。当段、亚段肺动 脉栓塞充盈缺损完全时,DEPI表现为肺段 或亚段分布灌注缺损,当部分充盈缺损 时,DEPI以灌注降低为主,少数表现为 无灌注缺损;利用DEPI诊断PE的敏感性 96.30%(52/54),特异性100%。结论 DEPI 表现与CTPA肺动脉栓塞程度、部位有关, 两者联合应用有助于提高肺动脉栓塞诊断 率,值得临床推广。

Objective To study the value of dual energy pulmonary angiography (DECTPA) with dual-source CT (DSCT) in pulmonary embolism (PE). Methods Collected the clinical data of 26 patients suspected of PE in our hospital underwent DECTPA with DSCT. Assessed the value of dual energy pulmonary angiography (DECTPA) with dualsource CT (DSCT) in pulmonary embolism (PE). Results The 96.30%, 90.57% agreement between DEPI and CTPA were showed in the levels of lung and partial lung respectively. Complete filling defects of segmental and subsegmental pulmonary arteries mostly showed correspon dence perfusion defects in the CT perfusion map. However, when there were partial filling defects, most of them were partial perfusion defects. A few of them were normal in the CT perfusion map. With CTPA as a reference standard,in the level o f lung, the results show that compared with DEPI, the sensitivity was 96.30% (52/54), specificity of 100% (76/76). Conclusion There was moderate agreement between the judgement of CTPA and DEPI. The perfusion defects in the DEPI related to the degree and location of the filling defects in the CTP A. The combination of CTPA and DEPI will offer more information for diagnosis of the pulmonary embolism. It is worth promotion in the clinical.

【关键词】双源CT;双能量成像;肺动脉栓塞;诊断

【中图分类号】R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.05.019

前言

肺动脉栓塞(Pulmonary embolism,PE)是一种由肺动脉及其分支 中栓子堵塞而引起的肺循环功能障碍综合征[1]。肺动脉栓塞是一种危 害性非常大并且比较常见的疾病,其高病死率给患者的健康和生命 带来了极大的威胁,且近年来其发病率呈上升趋势,因此,肺动脉 栓塞的及时诊断对疾病的治疗及预后具有重要意义[2]。目前影像学检 查是PE最主要的确诊手段[3],主要包括核素扫描、MRI、DSA和CT肺动 脉成像等,其中DSA被认为是诊断PE最准确的方法.但其属于有创检 查,并发症多,且重症患者无法检查,不宜首选。放射性核素检查 敏感性与特异性均较差,现今已很少运用。MRI检查肺栓塞的敏感度 可达70%~90%,但对外围型肺栓塞检出率较低,且对小的肺梗死、肺 实变的显示不如CT,同时MRI检查时间较长,重症患者难以耐受,费 用较高,故单纯的MRI检查应用较少。CT检查作为诊断PE的重要影像 手段,一直广泛应用于临床,其优势在于,CT的检查时间较短、空 间分辨率都较高;但CT肺动脉成像(computer tomograph pulmonary angiography,CTPA)对于亚亚段或者更远末梢的栓子的检出有所限制, 且难以评价肺实质血流的灌注情况[4]。而CT肺灌注成像可弥补CT肺动 脉成像的不足。   随着我国医疗水平的不断发展,双源CT(Dual-source Computer Tomography,DSCT-SOMATOM Definition,不断应用于临床。其主要的 优势在于:其凝聚了普通CT机的精髓[5],可同时显示肺组织的通气和 灌注[6],获得全肺的解剖和功能的双重信息[7]。但目前双源CT用于肺 栓塞诊断的报道较少[8]。我院关于双源CT双能量肺动脉成像检查的研 究,取得了较好的价值,现报道如下。