目的 分析尘肺灌洗治疗前后多 层螺旋CT表现及特点。方法 回顾性分析 我院收治的50例尘肺病患者的临床资料， 所有患者均接受大容量肺泡灌洗治疗及多 层螺旋CT检查，且影像学资料完整，统计 治疗前后患者肺容积、肺密度指标的改善 情况。结果 大容量肺泡灌洗后，患者全 肺容积、全肺含气体积略有上升，但与灌 洗前对比无统计学意义(P>0.05)，但灌洗 后，患者全肺重量减轻，平均肺密度降 低，平均肺体积上升，与灌洗前对比差异 有统计学意义(P<0.05)，以全肺重量变化 最为显著，其次为肺CT值、平均肺密度与 肺体积。结论 大容量肺泡灌洗后，尘肺 病患者多层螺旋CT定量定性指标肺密度、 肺容积的变化与肺功能指标的变化有其 较好的相关性，可作为患者疗效评估的依 据。

Objective To analyze the findings and characteristics of multi-slice spiral CT before and after lavage therapy of pneumoconiosis. Methods The clinical data of 50 patients with pneumoconiosis in Clinic were analyzed retrospectively. All patients were treated by large-capacity alveolar lavage and underwent multi-slice spiral CT examination and the imaging data were complete. The improvement of lung volume and lung density indexes in the patients before and after the treatment was statistically analyzed. Results After large-capacity alveolar lavage, total lung volume and total lung containing gas volume of the patients increased slightly but there was no statistical significance, compared with those before lavage (P>0.05). After lavage, the total lung weight was reduced, average lung density decreased and average lung volume increased. Compared with those before lavage, the differences were statistically significant (P<0.05). The changes of total lung weight were the most significant, followed by lung CT value, average lung density and lung volume. Conclusion After large-capacity alveolar lavage, the changes of multiple spiral CT quantitative and qualitative indexes such as lung density and lung volume and changes of pulmonary function indexes in patients with pneumoconiosis were well correlated, which can be used as the basis for the evaluation of the curative effect in patients.