Objective To analyze the effect of comprehensive nursing measures on postpartum urinary retention in painless parturients. Methods 60 cases of postpartum urinary retention of painless parturients admitted to our hospital from March 2015 to September 2017 were selected as the research objects. They were divided into routine group (30 cases, given routine nursing) and research group (30 cases, given comprehensive nursing). Observation and comparison of two groups of patients with nursing compliance and urination time. Results The total compliance rate was 96.67% in the study group and 80.00% in the routine group, which was significantly higher than that in the routine group (P<0.05). The incidence of urination time less than 4 hours in the study group was 66.67%, which was significantly higher than that in the routine group (36.67%) (P<0.05), while the incidence of 6-8 hours was significantly lower than that in the routine group (30.00%) (P<0.05). 0.05). Conclusion Comprehensive nursing can significantly reduce the incidence of postpartum urinary retention in painless parturients, promote patients'self-urination, and facilitate the recovery of postpartum women. The clinical effect is remarkable, which is worthy of clinical application and promotion.