Objective To observe and evaluate the clinical effect of tuberculosis combined with Western medicine in the treatment of cervical lymph node tuberculosis (CTL). Methods Eighty-six patients with cervical lymphatic tuberculosis were randomly divided into two groups. The control group was treated with traditional Chinese medicine in 43 cases. The observation group was treated with tuberculosis tablets in the control group. Clinical effect. Results The total effective rate of the observation group was 95.35%, which was significantly higher than that of the control group (79.07% (χ2 =5.1079, P=0.0000). The total adverse reaction rate of the observation group was 11.63%, which was significantly lower than that of the control group (34.88%) (χ2 =6.5152). P=0.0000), and the recurrence rate after 1a was significantly lower than that of the control group by 20.93% (χ2 =5.0260, P=0.0000). Conclusion Tuberculosis combined with Western medicine for the treatment of cervical lymph node tuberculosis (CTL) is safe and reliable, with remarkable curative effect, which can effectively reduce the incidence of adverse reactions and low recurrence rate.