Head and Neck Imaging
Clinicopathological of the Malignant Transformation of Bone Cyst
Author：CHENG Ke-lun
affiliation：Department of Pathology, Guizhou Aerospace Hospital, Zunyi 563000, Guizhou Province, China
PDFAbstract
Objective to study the clinicopathologic features of the malignant transformation of bone cyst. Methods Through conducting HE and immunohistochemical staining on a case study of malignant transformation of bone cyst, the histopathological features were observed, with relevant literature reviewed. Results It was firstly diagnosed as aneurysmal bone cyst, which showed malignant transformation after one year and nine months; the tumor was seen as a small round cell, with little cytoplasm, deep colored nucleus and unobvious nucleus division. Tumor cells showed diffused arrangement, with no chrysanthemum group structure and osteoid matrix. Immunophenotype: Vimentin diffusion (+), partial CD99 (+), P53 and little P16 (+). Conclusion The malignant transformation of bone cyst is rarely seen, and the histological characteristics and immunophenotype are the key points to make diagnosis. The first diagnosis for bone cyst should distinguish it from telangiectatic osteosarcomatosis and osteosarcoma with saccular aneurysm lesion.
【Keyword】Bone Cyst; Malignant Transformation; Pathology
【Chart number】R738.1
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2019.03.015
Journal of Rare Diseases
th26Volume， th 3 Issue
2019Year05Month
Related articles
Editor email：（1）中国CT和MRI杂志：ctmri@vip.163.com；（2）罕少疾病杂志：hs1999@vip.163.com
Contact number：0755-83695203
Our address：
English
简体中文
logged in
Wechat
TouTiao