Objective To investigate the clinical value of dual-source CT portography (CTPV) in observing collateral circulation of portal vein in hepatocirrhosis. Methods 80 patients with hepatocirrhosis diagnosed and treated in our hospital from March 2017 to March 2018 were selected as the study group, and 60 healthy people who received normal physical examination in our hospital during the same period were selected as the control group. The two groups underwent enhanced CT examination of upper abdomen and portal vein imaging, and the study group underwent gastroscopy. The main portal vein (MPV) and splenic vein of the two groups were measured respectively. (SPV), left branch of intrahepatic portal vein (IHLPV), right branch of intrahepatic portal vein (IHRPV) and left gastric vein (LGV) diameters and lower esophageal veins were compared and analyzed with Child-Pugh classification. Results CT portography can clearly show the collateral vessels in patients with hepatocirrhosis and portal hypertension. The diameter of portal vein branches and subordinate branches in the two groups was significantly different (P＜0.05). The mean diameter of collateral vessels in the study group was compared, and there were significant differences in different liver function grades (P＜0.05). CTPV and gastroscopy showed no significant difference in the detection ratio of lower esophageal varices, with Kappa greater than 0.75. Conclusion Dual-source CT portography can clearly show the portal vein and its collateral circulation in hepatocirrhosis patients, and it has a high value in judging the degree of liver function damage in hepatocirrhosis patients.