Sysrem Imaging
Study Dose Effect Relationship of Naloxone in the Clinical Treatment
Author：TU Xue-jun
affiliation：The Affiliated Hospital of Meizhou Medical College of Jiaying University, Meizhou 514031, Guangdong Province, China
PDFAbstract
Objective To study dose effect relationship of Naloxone in the treatment of clinical treatment. Methods From February 2011 to February 2015, 100 patients with cerebral infarction were randomly divided into four groups, 25 cases each. 1.2mg, Mg, 2.4mg, Mg, 3.6mg, Mg and 5.8mg mg doses of naloxone were administered to each group of patients. 15 days as a course of treatment, and observe the curative effect after a course of treatment. Results The 1.2mg group is almost ineffective, the 2.4mg group was in the rising phase of dose effect relationship. The 3.6mg group has good curative effect, but there is no obvious difference between the 5.8mg group. Conclusion According to the analysis of the dose effect curve, from 3.6 mg to 5.8 mg within the scope of use of naloxone in the treatment of cerebral infarction and the optimal dose.
【Keyword】Naloxone; Dose Effect Relationship; Cerebral Infarction
【Chart number】R543
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2017.05.025
Journal of Rare Diseases
th24Volume， th 5 Issue
2019Year11Month
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