Head and Neck Imaging
The Significance of MiRNA21 Expression in the Diagnosis of Gastric Cancer*
Author：YANG An, LI Xi.
affiliation：Department of Digestive Internal Medicine, Peking University Shenzhen Hospital, Shenzhen 518035, Guangdong Province, China
PDFAbstract
Objective To investigate the significance of the detection of miRNA21 expression in the serum and tissues of the patients with gastric cancer. Methods 20 patients with gastric cancer and 20 healthy controls were detected. And the expression of miRNA21 was evaluated by using the method of in situ hybridization and realtime quantitative polymerase chain reaction(PCR). Results miRNA21 in the serum and tissues of patients with gastric cancer was higher than that in the healthy control group, the difference had statistical significance (P<0.05). Conclusion The upregulated expression of miRNA21 in the serum and tissues of the patients with gastric cancer might provide a new direction of diagnosis and therapy for gastric cancer.
【Keyword】Gastric Cancer; miRNA21
【Chart number】R735.2
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2018.05.027
Journal of Rare Diseases
th25Volume， th 5 Issue
2019Year11Month
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