Objective To investigate the clinic effect of diversified health education on treatment compliance and life quality in patients with new low hematodialysis. Methods 60 cases with new low hematodialysis in our hospital from July 2016 to July 2017 were selected and number according to admission time, first 30 cases given common nursing were seen as control group, another 30 cases given diversified health education were seen as observation group. Treatment compliance and life quality of the two groups after treatment were compared. Results After different nursing, mental ability, body ability,social capability, material life condition of observation group were obviously higher than control group; treatment compliance of observation group (100.00%) was significantly higher than control group (50.00%), the difference was statistic significant (P<0.05). Conclusion The application of diversified health education on patients with new low hematodialysis can significantly improve treatment compliance and life quality.