Objective To explore the therapeutic effect of nursing intervention on traumatic hemopneumothorax during emergency treatment. Methods From Mar. 2014 to Mar. 2017, 60 patients with traumatic hemopneumothorax in our emergency department were randomly divided into observation group (n=30) and control group (n=30). The control group was given routine emergency nursing intervention, and the observation group was given comfort nursing intervention. The VAS scores, nursing effective rates and total satisfaction rates of nursing in the two groups were compared. Results After the intervention, the VAS score in the observation group was(2.56±0.68) which was significantly lower than that in the control group(6.45±1.01), the difference was statistically significant (P<0.05), the nursing effective rate and total satisfaction rate of nursing in the observation group were 96.67% and 100.00% which were significantly higher than those in the control group 76.67% and 83.33%, and their differences were statistically significant (P<0.05). Conclusion Comfort nursing intervention which has obvious effect on traumatic hemopneumothorax during emergency treatment, can not only significantly improve the nursing effect and nursing satisfaction , but also relieve the pain of patients.