Objective To explore the influence of integrated nursing mode during pregnancy on breastfeeding patterns in puerpera. Methods From Jan. 2014 to May 2015, 216 cases of puerpera in our hospital were taken as the research objects, and they were randomly divided into the integrated nursing group (experimental group, n=108) and traditional nursing group (control group, n=108). The differences of breast-feeding patterns and incidence rates of adverse reactions of breast between the two groups were observed and compared. Results There was no significant difference between the two groups in the mixed feeding rate (P>0.05), the pure breastfeeding rate in the experimental group was higher than that in the control group (P<0.05), and the rate of artificial feeding in the experimental group was lower than that in the control group (P<0.05). The incidence rates of breast tenderness, cracked nipple and galactostasis in the experimental group were lower than those in the control group (P<0.05). Conclusion Integrated nursing mode can not only improve the proportion of breastfeeding through systematic education and guidance, but also reduce the risk of breast discomfort in postpartum breast-feeding women.