Objective To analyze the application of glucocorticoid inhalation therapy in children with bronchial asthma clinical effect of the treatment process. Methods 100 cases of bronchial asthma were selected in our hospital between September 2014 -2016 period in May, according to the time of admission of children and parents will, divided into observation group and control group, each group of 50 cases. The control group was treated with salbutamol and ipratropium bromide saline atomization treatment, observation group received routine treatment and budesonide inhalation treatment, clinical curative effect of the two groups were compared. Results The two groups of children lung function before treatment was no significant difference, that the corresponding data comparison, P> 0.05, there is no statistically significant; but the two groups of children treatment, lung function in children was significantly better than the observation group children in the control group, the corresponding data between groups were compared, P <0.05, statistically significant differences; children with clinical observation group was 92.00%, the clinical treatment of children with the control group was 74.00%, two sets of data were compared, differences between the groups P <0.05, significant difference has obvious nature. Conclusion Children with bronchial asthma clinical treatment, treated with budesonide inhalation therapy can effectively improve lung function in patients, improve the patient's clinical curative effect, promote early rehabilitation, is conducive to the normal growth and development of children, and is worthy of clinical application and popularization value.