摘要
目的 研究静滴缩宫素对胎儿脐血血气分析结果产生的影响。方法 选取2016年10月-2017年3月我院72例妊娠孕妇 纳入研究,按照随机数字表法分2组,每组36例,A组分娩过程中静滴缩宫素,B组未予以缩宫素,比较2组胎儿脐 血血气分析结果。结果 A组血糖(2.14±0.20)mmol/L、血氯(92.13±3.14)mmol/L、血钠(130.27±3.42)mmol/L、 PH值(7.09±0.08),明显低于B组血糖(2.63±0.38)mmol/L、血氯(98.72±1.73)mmol/L、血钠(139.28±3.97) mmol/L、PH值(7.28±0.07)(P<0.05),且胆红素(28.36±3.75)mg/L、BE(0.28±0.11)mmol/L,明显高于B组 (12.64±2.13)mg/L、BE(0.14±0.05)mmol/L;A组新生儿高胆红素血症发生率63.89%,明显高于B组33.33%(P <0.05)。结论 妊娠孕妇分娩过程中静滴缩宫素,较易引起新生儿低糖、低钠或者低氯血症,降低血PH值,提高胆 红素水平以及BE,增加新生儿高胆红素血症与酸中毒风险,因而临床上需合理应用缩宫素。
Objective To study the effect of oxytocin on blood gas analysis of fetal cord blood. Methods From Oct. 2016 to Mar. 2017, a total of 72 pregnant women in our hospital were taken as the clinical objects, which were randomly divided into A group (36 cases) and B group (36 cases). In the process of delivery, only A group was given oxytocin. The blood gas analysis of fetal cord blood in the two groups was compared. Results The blood glucose, blood chlorine, blood sodium and pH value in the A group were respectively(2.14±0.20)mmol/L,(92.13±3.14)mmol/L,(130.27±3.42) mmol/L and(7.09±0.08) which were obviously lower than those in the B group(2.63±0.38)mmol/L,(98.72±1.73)mmol/ L,(139.28±3.97)mmol/L and (7.28±0.07)(P<0.05), the bilirubin and BE in the A group were respectively(28.36±3.75) mg/L and(0.28±0.11)mmol/L which were obviously higher than those in the B group (12.64±2.13)mg/L and (0.14±0.05) mmol/L. The incidence rate of neonatal hyperbilirubinemia in the A group was 63.89% which was obviously higher than that in the B group 33.33%(P<0.05). Conclusion In the process of delivery, intravenous oxytocin can cause neonatal hypoglycemia, hyponatremia or hypochloraemia, reduce the blood pH value, raise the level of bilirubin and BE, increase the risk of neonatal hyperbilirubinemia and acidosis. Therefore, oxytocin should be rationally applied in clinic.
【关键词】缩宫素;胎儿脐血;血气分析
【中图分类号】R714
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.01.020
前言
缩宫素属于合成多肽激素,使用半衰期通常为 3~5min,对产妇静滴3~5min能够促进子宫平滑肌收 缩,为临床常用加强妊娠孕妇子宫收缩药物,益于分 娩,特别是妊娠足月子宫,对缩宫素具有极高敏感 性[1-2]。本文以72例妊娠孕妇作为研究对象,探讨静 滴缩宫素对胎儿脐血血气分析结果产生的影响,现汇 报如下。
罕少疾病杂志
第25卷, 第 1 期
2019年11月
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