论著-头颈部
综合排痰辅助治疗小儿哮喘样支气管炎效果观察及对患儿气道高反应性的预防分析
作者:郭 楠1 张 梦2
所属单位:1.河南省开封市儿童医院急诊科(河南 开封 475000)2.河南省开封市卫生学校 (河南 开封 475000)
PDF摘要
目的 探究综合排痰辅助治疗小儿哮喘样支气管炎的效果及对患儿气道高反应性的影响。方法 随机选取2015年5 月-2017年1月我院门诊收治的哮喘样支气管炎患儿80例为研究对象,按治疗方式不同将其分为观察组(n=40)和对照 组(n=40),对照组患儿采用常规治疗和护理。观察组患儿在对照组基础上联合综合排痰辅助治疗,比较两组临床疗 效、炎症因子水平和治疗前后肺功能指标变化、PC20FEV1(FEV1下降20%需要激发药物的浓度)。结果 观察组疗效总有 效率(92.5%)显著高于对照组(72.5%),治疗后观察组炎症因子水平显著低于对照组,观察组治疗后肺功能指标和 PC20FEV1水平显著高于对照组,差异具有统计学意义(P<0.05)。结论 综合排痰辅助治疗小儿哮喘样支气管炎能显著 减轻患儿气道炎症反应,改善肺功能,降低气道高反应性,值得推广。
Objective To investigate the effect of comprehensive expectoration adjunctive therapy on asthmatic bronchitis and its influence on airway hyperreactivity in children. Methods From May 2015 to Jan. 2017, 80 cases of children with asthmatic bronchitis in our hospital were selected as the research objects, and they were divided into observation group (n=40) and control group (n=40) according to their different treatment methods. The control group was given routine treatment and nursing, and the observation group was given additional comprehensive expectoration adjunctive therapy on the basis of the control group. The curative effects, inflammatory factors levels and pulmonary function changes before and after treatment, PC20FEV1 (FEV1 down 20% required the concentration of drug to be stimulated) in the two groups were compared. Results The total effective rate in the observation group was (92.5%) which was significantly higher than that in the control group (72.5%), after treatment, the levels of inflammatory factors in the observation group were significantly lower than those in the control group; the lung function indexes and the level of PC20FEV1 in the observation group after treatment were significantly higher than those in the control group, the difference was statistically significant (P<0.05). Conclusion Comprehensive expectoration adjuvant therapy can significantly not only reduce airway inflammation and airway hyperreactivity, but also improve lung function for children with asthmatic bronchitis. Thus, it is worthy of promotion.
【关键词】综合排痰;哮喘性支气管炎;效果;气道高反应性
【中图分类号】R562.2+1
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.01.012
前言
哮喘样支气管炎(又称喘息样支气管炎)是一组以 反复发作的喘息主要表现的婴幼儿急性支气管炎,与 患儿过敏体质和呼吸道感染有关,多发于3岁以下婴 幼儿,病程较长且有反复发作史[1-2]。哮喘样支气管 炎发作时,可导致患儿气道痰液增加且无法正常排 出,阻塞气道,并发呼吸困难、低氧血症、二氧化碳 潴留、意识障碍甚至昏迷、急性呼吸衰竭等严重并发 症致患儿死亡[3-4]。因此,排痰治疗对缓解哮喘样支气管炎患儿的临床症状具有重要作用。本研究旨在探 究综合排痰辅助治疗小儿哮喘样支气管炎的效果及对 患儿气道高反应性的影响,现报道如下。
罕少疾病杂志
第25卷, 第 1 期
2019年11月
相关文章