目的 回顾分析一例伴有ANCA(+)的结节性多动脉炎导致肾脏损害病例的临床特点、诊治经验及诊疗流程，并就结节 性多动脉炎进行文献复习。方法 本例ANCA(+)确诊为PAN致肾脏损害的患者通过肾脏穿刺活检、血清学等检查进行 早期诊断，及时给予免疫抑制治疗。结果 本例患者肾脏恢复良好，定期随访，脱离透析。结论 结节性多动脉炎可 出现ANCA(+),老年急性肾损伤患者需要警惕结节性多动脉炎，积极的免疫抑制治疗有助于改善预后。

Objective To investigate the clinical characteristics, diagnosis and treatment of 1 case of acute kidney injury induced by polyarteritis nodosa with ANCA(+) in an old male, and to review the literatures about diagnosis and treatment of polyarteritis nodosa. Methods Early diagnosis was performed with the renal biopsy and the laboratory examinations. The patient was treated with the immunosuppressive therapy in time. Results The patient recovered well, urine output became normal, renal function improved. He was away from dialysis. Conclusion Polyarteritis nodosa can go with ANCA(+).Elderly patients with acute kidney injury need to be excluded polyarteritis nodosa. Active immunosuppressive therapy is helpful to improve the prognosis.