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·胸部疾病·

超声心动图对尿毒症血透患者在透析前后心脏结构与功能改变的研究

作者:郭佳妮

所属单位:广西省南宁市第一人民医院超声科 (广西 南宁 530022)

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摘要

目的 研究分析超声心动图在尿毒症血透患者透析前后心脏结构与功能改变中的应用价值。方法 选取2014年4 月-2016年1月在我院进行诊治的80例尿毒症血透患者,所有患者均于血透前后给予超声心动图检查,对比分析患者 治疗前后心脏结构与功能改变情况。结果 透析6个月后患者心结构指标LAD及LVEDD较治疗前无明显变化(P>0.05), LVPM、ISVD、LVMI则较治疗前明显降低(P<0.05),心功能指标CO、SV、E、A、E/A较治疗前无明显变化(P>0.05), LVEF、FS、TEI则较治疗前明显改善(P<0.05)。结论 超声心动图应用于尿毒症血透患者透析前后,有助于对尿毒症 心功能损害程度做出早期判断,有效评价血透后心脏结构及功能变化情况。

Objective To study the application value of echocardiography through changes of cardiac structure and function in patients before and after dialysis in uremic patients. Methods 80 cases of uremia blood in April 2014-2016 year in January in our hospital for diagnosis and treatment of hemodialysis patients, all patients before and after hemodialysis with echocardiography, comparative analysis of patients before and after the change of cardiac structure and function. Results After 6 months of dialysis LAD and LVEDD index in patients with cardiac structure than before treatment had no significant change (P>0.05), LVPM, ISVD, LVMI were significantly lower than that before treatment (P<0.05), heart function index of CO, SV, E, A, E/A compared with before treatment, no significant changes (P>0.05), LVEF, FS, TEI were significantly improved compared with before treatment (P<0.05). Conclusion The use of echocardiography in hemodialysis patients before and after dialysis, helps to make early judgment on heart function in uremic hemodialysis can effectively evaluate the extent of the damage, after the heart Structure and function changes.

【关键词】超声心动图;尿毒症;血液透析;心脏结构;心脏功能

【中图分类号】R540.4+5

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2017.02.015

前言

血液透析(HD)是尿毒症发展至终末期时常用治疗 手段,其可在较段时间内将血液中的毒素清除,降低 容量负荷,缓解出血倾向,目前已在临床得到广泛应 用。但有研究发现[1],心血管病变是导致尿毒症患者 死亡主要原因之一,而在开展血液透析的尿毒症患者 中,80%以上患者在血透期间发生心血管事件,导致 心脏结构及功能改变。近年来,超声心动图在临床心 脏功能检查中广泛应用,其可清楚显示患者心肌形 态,心脏结构以及心肌舒张、收缩功能,可对心脏病 变程度进行早期评估。对我院尿毒症患者透析前及透 析后6个月时的超声心动图进行比较,以探讨其在心 脏结构和功能检查中的应用价值,为以后临床检查提供参考,现报告如下。