目的 探讨经颅彩色多普勒与颈动脉超声联合运用在糖尿病患者脑动脉硬化评估中的临床价值。方法 选取2013年 3月-2015年2月收治的糖尿病患者120 例为研究对象，另选同期行健康检查者120例为对照组，对两组对象进行经 颅彩色多普勒与颈动脉超声检查，观察两组对颈总动脉内中膜厚度(IMT)、阻尼指数(RI)及搏动指数(PI)，糖尿 病患者根据IMT分组，IMT≥1.0mm为增厚组，IMT＜1.0mm为未增厚组，对各组对象左、右侧椎动脉及基底动脉平 均血流速度进行检测。结果 观察组患者颈总动脉IMT、RI、PI同对照组比较，均显著较高，差异有统计学意义(P ＜0.05)，观察组患者中，IMT≥1.0mm者23例，IMT＜1.0mm者97例；增厚组患者左、右侧椎动脉及基底动脉平均血 流速度同未增厚组及对照组比较，均明显较低，差异有统计学意义(P＜0.05)。结论 经颅彩色多普勒联合颈动脉超 声可有效评估糖尿病脑动脉硬化，利于脑血管意外防治，值得推广。

Objective To investigate the clinical value of transcranial color Doppler ultrasonography combined with carotid artery ultrasonography in the evaluation of cerebral arteriosclerosis in patients with diabetes mellitus. Methods 120 patients with diabetes mellitus and 120 cases who took health examination in hospital from March 2013 to February 2015 were included as the observation group and the control group. Transcranial color Doppler ultrasonography and carotid artery ultrasonography were applied in both group. The intima-media thickness (IMT), resistance index (RI) and pulsatility index (PI) of both groups were observed. According to IMT, The observation group were divided into thickening group (IMT≥1.0mm) and non-thickening group (IMT<1.0mm), the average blood flow velocity of left and right vertebral artery and basilar artery in each group were detected. Results IMT, RI and PI of carotid artery in the observation group were significantly higher (P<0.05) than in the control group. There were 23 cases with IMT≥1.0mm and 97 cases with IMT<1.0mm in the observation group. The average blood flow velocity of left and right vertebral artery and basilar artery in thethickening group were significantly slower (P<0.05) than in the non-thickening group and control group. Conclusion Transcranial color Doppler ultrasonography combined with carotid artery ultrasound can effectively assess the cerebral artery atherosclerosis in patients with diabetes, which is conducive to the prevention and treatment of cerebral vascular disease, it is worth promoting.