目的 研究丁苯酞氯化钠注射液对进展性脑梗死患者双抗血小板疗效及神经缺损功能恢复的影响。方法 纳入106例 进展性脑梗死患者为治疗对象，根据治疗用药不同，随机分为对照组（n=53）和治疗组（n=53），对照组给予氯 吡格雷片+阿司匹林肠溶片双重抗血小板治疗，治疗组在对照组治疗基础上加用丁苯酞氯化钠注射液治疗，比较两 组NHISS评分与Barthel指数、治疗疗效和不良反应。结果 治疗后，两组NHISS评分显著降低（P<0.01），Barthel 指数显著上升（P<0.01），且治疗后治疗组下降或上升幅度显著高于对照组（P<0.01）；治疗组治疗总有效率 86.79%，对照组67.92%，两组差异显著（P<0.05）；两组均未出现不良反应。结论 丁苯酞氯化钠注射液联合双抗 血小板治疗进展性脑梗死，可显著改善患者神经功能缺损状态，提高生活质量，治疗效果显著，具临床推广意义。

Objective To study the effect of butylphthalide and sodium chloride injection on dual antiplatelet therapy and recovery of neurologic impairment in patients with progressive cerebral infarction. Methods A total of 106 patients with progressive cerebral infarction were taken as the clinical research objects, and they were randomly divided into control group (53 cases) and treatment group (53 cases). Both groups were given dual antiplatelet therapy with clopidogrel and aspirin enteric-coated tablets, besides, the treatment group was given additional butylphthalide and sodium chloride injection. The NHISS scores, Barthel indexes, treatment effects and adverse reactions in the two groups were compared. Results After treatment, the NHISS scores in the two groups were obviously decreased (P<0.01), Barthel indexes in the two groups were obviously increased (P<0.01), the decrease or increase range in the treatment group was higher than that in the control group (P<0.01), the total effective rate of the treatment group was 86.79% which was higher than that of the control group 67.92%, and their difference was statistically significant (P<0.05), there was no adverse reaction in the two groups. Conclusion Butylphthalide and sodium chloride injection combined with dual antiplatelet therapy whose treatment effect is significant, can obviously improve neurological function and life quality for patients with progressive cerebral infarction.Thus, it is worthy of promotion.