摘要
目的 探讨在妊娠期高血压患者中采用拉贝洛尔与硫酸镁联合进行治疗对妊娠结局的影响。方法 选取2014年4 月-2016年4月我院收治的58例妊娠期高血压患者,根据住院顺序随机分为实验组和对照组,每组各29例患者。对照 组患者通过硫酸镁进行治疗,实验组患者通过拉贝洛尔与硫酸镁联合进行治疗,对比两组患者血压情况、分娩方式 以及新生儿结局。结果 两组患者在治疗后血压均有明显的下降,但是实验组患者治疗后的血压值低于对照组,两 组患者间差异有统计学意义(P<0.05)。实验组患者的自然分娩率明显高于对照组患者,两组患者自然分娩率间的 差异有统计学意义(P<0.05)。实验组早产率、宫内窘迫率以及新生儿窒息率均明显低于对照组,两组间差异有统 计学意义(P<0.05)。结论 在妊娠期高血压患者中采用拉贝洛尔与硫酸镁联合进行治疗,有效地降低了患者的血 压,提高了自然分娩率,也改善了新生儿结局情况,值得在临床上进行推广应用。
Objective To study in patients with hypertension in pregnancy with labetalol and Magnesium Sulfate joint treatment on the outcome of pregnancy. Methods 58 cases of patients with gestational hypertension from April 2014 -2016 year in April in our hospital, according to the order of hospitalization were randomly divided into experimental group and control group, 29 patients in each group. The patients in the control group through the treatment of patients in the experimental group by Magnesium Sulfate, Magnesium Sulfate and labetalol combined therapy, compared two groups of patients with blood pressure, mode of delivery and neonatal outcomes. Results the two groups after treatment in patients with blood pressure significantly decreased, but experimental group after treatment in patients with blood pressure lower than the control group, two groups of patients with obvious differences (P<0.05). The patients in the experimental group the natural birth rate was significantly higher than the control group. The difference between the two groups in the rate of natural childbirth was significantly (P<0.05). The experimental group of preterm birth Rate, intrauterine distress rate and the rate of neonatal asphyxia were significantly lower than those in control group. Between the two groups significant difference (P<0.05). Conclusion In patients with pregnancy induced hypertension in the labetalol and magnesium sulfate combined therapy, effectively reduces the patient's blood pressure, increase the natural delivery rate, but also improve the neonatal outcome, it is worthy of popularization and application in clinic.
【关键词】拉贝洛尔;硫酸镁;妊娠期;高血压;妊娠结局
【中图分类号】R714.25;R972+.4
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2016.06.016
前言
在临床上,妊娠期高血压的症状主要为高血压、 尿蛋白以及水肿,这是一种比较常见的孕妇并发症 [1]。在妊娠20周之后该病的发病率比较高,可以导致 孕妇胎盘早剥以及早产,严重时会造成流产,对母婴 安全产生了比较严重的威胁[2]。所以,对妊娠期高血 压进行有效地治疗就显得十分有意义。为了探讨在妊 娠期高血压患者中采用拉贝洛尔与硫酸镁联合进行治 疗对妊娠结局的影响,本次研究选取了我院收治的58例妊娠期高血压患者来作为研究对象,获得了很好的 临床效果,报道如下。
罕少疾病杂志
第23卷, 第 2 期
2019年11月
相关文章