目的 探讨综合性护理干预在降低新生儿机械通气感染率中的临床效果。方法 选取我院2013年2月至2015年2月期间 接收治疗的100例行机械通气治疗的新生儿作为研究分析对象，将所选患儿按本次治疗护理方式分为对照组和研究 组(患儿家属均明确本次护理方案，并签字确认)，每组各50例，对照组采用常规护理方式，研究组采用综合性护理 方式，护理后，比较两组患儿临床状况。结果 比较两组患儿护理后各指标状况，包含死亡率、VAP发生率、院内感 染率等三个方面，研究组均明显低于对照组，且数据存在一定差异，具有统计学意义(P<0.05)。结论 综合性护理 干预可全面重点防控新生儿机械通气感染有关因素，此护理方式可降低新生儿机械通气感染率和死亡率等，其临床 应用价值较大。

Objective To analyze the effect of comprehensive nursing intervention on reducing the infection rate of neonatal mechanical ventilation. Methods From Feb. 2013 to Feb. 2015, a total of 100 neonates who accepted mechanical ventilation in our hospital were taken as the clinical research objects, and they were divided into study group(50 cases) and control group(50 cases). Patients in the control group accepted traditional nursing, the other patients in the study group accepted comprehensive nursing (this program was confirmed and signed by the family members of children) in order to compare their clinical effects. Results After nursing, the indicators such as mortality rate, incidence of VAP and nosocomial infection rate in the study group were remarkably lower than those in the control group, and their differences were statistically significant (P<0.05). Conclusion Comprehensive nursing intervention which can fully focus on the prevention and control of neonatal mechanical ventilation infection related factors has the advantage of reducing infection and mortality rate of neonatal mechanical ventilation. Thus, it is worthy of clinical application.