目的 MRI与三维超声在产前胎儿 畸形筛查中的应用。方法 选择2016年1月 到2018年1月到医院进行产检孕妇90例， 所有孕妇均进行三维超声及MRI检测。比 较三维超声及MRI检出效能，统计两种检 测方式对不同部位畸形胎儿检出率，统计 两种检测方式对不同类型畸形胎儿检出 率。结果 三维超声诊断胎儿畸形准确率 86.67%、灵敏度89.16%、特异度57.14%， MRI诊断胎儿畸形准确率92.22%、灵敏度 93.98%、特异度71.43%；随访结果显示 共有131处畸形，MRI在颅面部、腹部处畸 形、神经系统畸形、泌尿系统畸形检出率 高于三维超声检测，差异有统计学意义(P ＜0.05)。结论 MRI在产前胎儿畸形筛查 中检出率更高。

Objective To explore the application of MRI and three-dimensional ultrasound in the screening of prenatal fetal malformation. Methods A total of 90 cases of pregnant women who admitted to the hospital for production inspection from January 2016 to January 2018 were enrolled. All pregnant patients were given three-dimensional ultrasound and MRI. The detection efficiency of three-dimensional ultrasound and MRI were compared, and the detection rates of two detection methods for malformed fetuses in different parts were counted, and the detection rates of different types of malformed fetuses were counted. Results The accuracy rate, sensitivity and specificity in the diagnosis of fetal malformation were 86.67%, 89.16% and 57.14% by three-dimensional ultrasound, and were 92.22%, 93.98% and 71.43% by MRI. The follow-up results showed that there were 131 malformations, and the detection rates of MRI in craniofacial malformation and abdomen malformation were higher than those of three-dimensional ultrasound (P<0.05). The detection rates of MRI in the nervous system malformation and urinary system malformation were higher than those of three-dimensional ultrasound (P<0.05). Conclusion MRI has a high detection rate in prenatal fetal malformation screening.