论著-头颈部
重症腺病毒肺炎患 儿临床特征及CT诊 断分析*
作者:李 晶1 岳学静2 郭喜霞1 仼一帅1 李树军3
所属单位:1.新乡医学院第一附属医院小儿内 科三病区 (河南 卫辉 453100) 2.新乡医学院 (河南 新乡 453003) 3.新乡医学院第一附属医院PICU (河南 卫辉 453100)
PDF摘要
目的 研究重症腺病毒肺炎患儿 临床特点及CT诊断结果。方法 将我院 2016.12至2017.12间收治的154例腺病毒 肺炎患儿纳为研究对象,分析临床表现 及其CT诊断特征。结果 ①腺病毒肺炎患 儿男女比例为1.96:1,年龄集中在6个 月-2岁(79.22%),发病季节集中在春冬季 (71.43%),治疗效果一般较好;主要临 床症状有发热、咳嗽、气喘等,89.64% 与61.04%的患儿存在肺部湿罗音与肺部哮 鸣音;实验室检查提示86.36%的患儿肌酶 谱升高,50.65% CRP升高,40.26% WBC 升高;②将患儿分为普通组(普通型腺病 毒肺炎,n=104)与重症组(重症腺病毒, n=50),重症组与普通组患儿X线片均有双 肺纹理改变、肺气肿、小叶实质浸润等病 变,但重症腺病毒肺炎患儿肺气肿、单侧 实变分布、肺段及大叶实质浸润情况均较 普通腺病毒肺炎患儿严重;重症组与普通 组患儿胸部CT检查均有肺实质改变、双肺 受累、实变向心性分布、小气道改变等, 但重症腺病毒肺炎患儿双肺受累、受累肺 叶数≥3、实变向心性分布、团簇状影、 支气管充气征、小气道改变程度及胸膜增 厚情况均较普通组严重。结论 重症腺病 毒感染X线片以肺间质改变、实变、小叶 实质浸润与肺段及肺叶实质浸润居多,CT 以双肺多发团簇状实质为特点,病变密度 多较高,具有边缘模糊、强化均匀的特 点,且多呈向心性分布,且小气道改变情 况较为严重。
Objective To study the clinical characteristics and CT diagnosis results of children patients with severe adenovirus pneumonia. Methods A total of 154 children patients with adenoviral pneumonia admitted to our hospital from December 2016 to December 2017 were included in the study. The clinical manifestations and CT diagnostic features were analyzed. Results The ratio of male to female in children patients with adenovirus pneumonia was 1.96:1, and the age was concentrated in 6 months to 2 years (79.22%), and the onset season was concentrated in spring and winter (71.43%), and the treatment effect was generally good. The main clinical symptoms were fever, cough and asthma, and 89.64% and 61.04% children patients had lung wet rales and lung wheezing rales. Laboratory tests showed that 86.36% children patients had elevated muscle zymogram, and 50.65% with increased CRP and 40.26% with elevated WBC. Children patients were divided into general group (general adenovirus pneumonia, n=104) and severe group (severe adenovirus pneumonia, n=50). X-ray films of severe group and general group were with lung texture changes, emphysema and lobular parenchymal infiltration, but the emphysema, unilateral consolidation, lung segment and large leaf parenchymal infiltration in children patients with severe adenovirus pneumonia were more severe than those in children patients with general adenovirus pneumonia. Chest CT examinations of severe group and general group showed lung parenchyma changes, double lungs involvement, consolidation and centripetal distribution and small airway changes. However, the double lungs involvement, involved lung lobes ≥3, and consolidation and centripetal distribution, cluster-like shadow, air bronchogram, small airway change and pleural thickening in children patients with severe adenovirus pneumonia were more severe than those in general group. Conclusion X-ray films of severe adenovirus infection have pulmonary interstitial changes, consolidation, lobular parenchymal infiltration and infiltration of lung and lobes. CT is characterized by multiple cluster-like parenchyma of double lungs, and the parenchyma have high density, fuzzy edges and uniform enhancement, and they are
【关键词】重症腺病毒肺炎;临床特征; CT诊断分析
【中图分类号】R563.1;R814.42
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2019.03.001
前言
腺病毒(adenovirus,ADV)是导致小儿肺炎及重症肺炎的主要致病 菌之一,重症肺炎并发症多,且累及多脏器,是造成小儿死亡的重要 病因[1]。及早确诊并采取相关治疗是挽救患儿生命健康的有效前提, 临床工作中,我们将肺部湿罗音作为重度腺病毒肺炎诊断依据之一, 但肺部病征出现时间较晚,易耽误患儿早期治疗[2]。影像学检查方式 能灵敏评估肺部病变,帮助患儿及早确诊,对其治疗及预后均有重要 意义[3]。本文研究重症腺病毒患儿临床表现及胸部CT诊断特征,旨在 为临床确诊重症腺病毒提供参考。
中国CT和MRI杂志
第17卷, 第 3 期
2019年03月
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