摘要
目的 分析双时相三维稳态进动 快速成像序列(3D SSFP)对先天性心脏 (CHD)大血管畸形的诊断价值。方法 对 我院近两年(2015年12月-2017年12月)收 治的经超声诊断为CHD的46例患者先心病 患者在术前或术后均采用胸部双时相3D SSFP成像及传统对比剂增强磁共振血管成 像(CE-MRA)技术,比较两种MR检查获得的 先心病患者大血管图像质量及测得的大血 管直径,分析评估双时相3D SSFP成像技 术在先天性心脏(CHD大血管畸形中的诊断 效能。结果 两种MR检查获得的先心病患 者大血管图像质量无显著差异(P>0.05); 3D SSFP收缩期、舒张期及CE-MRA测得的 主动脉、左肺动脉、右肺动脉直径差异显 著(P<0.05),肺总动脉及下腔静脉直径无 显著差异(P>0.05),3D SSFP收缩期测得 的主动脉、肺总动脉、右肺动脉直径显著 大于舒张期(P<0.05),左肺动脉及下腔静 脉直径与舒张期无显著差异(P>0.05)。结 论 3D SSFP成像技术能清晰显示先天性心 脏病患者的大血管形态变化,且能准确测 量不同心动时期大血管直径,有助于临床 制定合理的治疗方案,提高CHD患者的治 疗效果。
Objective To analyze the diagnostic value of dual-phase three-dimensional steady-state precession (3D SSFP) in large vessels malformations of congenital heart disease(CHD). Methods A total of 46 cases of patients with congenital heart disease (CHD) diagnosed by ultrasound in our hospital in the past two years (December 2015 to December 2017) were treated with chest dual-phase 3D SSFP imaging and traditional contrast enhanced magnetic resonance angiography (CE-MRA) technique before or after surgery. The large vessels image quality and measured large vessels diameters of CHD patients were compared between the two MR examinations, and the diagnostic efficacy of dual-phase 3D SSFP imaging in large vessels malformations of CHD was analyzed and evaluated. Results There was no significant difference in the large vessels image quality in CHD patients between the two MR examinations (P>0.05). There were significant differences in the diameters of aorta, left pulmonary artery and right pulmonary artery measured by 3D SSFP in systolic phase and diastolic phase and CE-MRA (P<0.05), and there was no significant difference in the diameters of common pulmonary artery and inferior vena cava (P>0.05). The diameters of aorta, common pulmonary artery and right pulmonary artery measured by 3D SSFP in systolic phase were significantly larger than those in diastolic phase (P<0.05), and there was no significant difference in the diameter of left pulmonary artery and inferior vena cava compared with those in diastolic phase (P>0.05). Conclusion 3D SSFP imaging can be used to the diagnosis of large vessels morphology of patients with congenital heart disease, and can measure the diameters of large vessels in different cardiac phases accurately, and it helps to develop a reasonable treatment regimen and improve the treatment effects of CHD patients.
【关键词】先天性心脏病;磁共振血管成 像;3D SSFP;大血管直径; 图像质量
【中图分类号】R541.1;R445.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.03.007
前言
先天性心脏病(Congenital Heart Disease,CHD)是指胚胎发育时 期心脏及大血管形成障碍或发育障碍所致心脏畸形[1]。据流行病学统 计,我国每年约有15万新生儿出现CHD,1/3新生儿因未接受及时合理 治疗而死亡,死亡率最高的四种CHD类型依次为大动脉转位、房间隔缺 损、动脉导管未闭、肺动脉瓣狭窄[2],故提高CHD大血管畸形的检出率 至关重要。目前,临床对CHD的诊断多依赖影像学检查,超声和CT是 CHD最常用的检查手段,磁共振(MR)因对心外大血管结构异常的显示具 有较大的优势在CHD的诊断中越来越广泛[2-3]。传统的MR检查对操作者 技术及受检者配合度要求较高,而部分CHD患者屏气效果差扫描的图像 质量不能满足诊断要求,增强磁共振血管成像(CE-MRA)虽需要受检者 注射造影剂,肾功能不全的患者不宜使用[3]。非对比剂增强血管成像 技术的发展为CHD的诊断带来了新的希望,其中双时相三维稳态进动快 速成像序列(3D SSFP)因无需对比剂,简单无创,成本低在先心病的诊 断中运用越来越广泛[4],本次研究对CHD患者3D SSFP及CE-MRA两种扫 描图像进行分析,旨在探讨3D SSFP在CHD大血管中的诊断价值,为临 床CHD诊治提供可靠的影像依据,具体如下。
中国CT和MRI杂志
第17卷, 第 3 期
2019年03月
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