目的 分析卵巢肿瘤MRI定量诊 断的临床价值。方法 选取2015年6月至 2018年6月我院91例卵巢肿瘤病例资料， 均于我院接受MRI检查，并行手术治疗， 依据病理结果将其分为恶性组(n=35，病 理证实为卵巢恶性肿瘤)、良性组(n=56， 病理证实为卵巢良性肿瘤)，分析两组 影像特点、MRI定量参数[容量转移常数 (Ktrans)、速率常数(Kep)、血管外细胞间 隙容积比(Ve)]、表观扩散系数(ADC)值， 比较不同分期患者上述指标，分析定量参 数、ADC区分良恶性卵巢肿瘤的效能。结 果 良性组Ktrans、Kep、Ve低于对照组，而 ADC值高于对照组(P＜0.05)，良性组以 Ⅰ型(流入型)为主，恶性组以Ⅲ型(流出 型)为主；随FIGO分期增加，卵巢恶性肿 瘤患者Ktrans、Kep、Ve增加，ADC值下降(P ＜0.05)；定量参数中，Ktrans诊断卵巢恶 性肿瘤的AUC值、特异度、最大约登指数 最大，ADC、Kep次之，Ve最小，ADC诊断卵 巢恶性肿瘤的灵敏度最高。结论 MRI定量 参数为常规MRI诊断卵巢肿瘤、准确进行 临床分期的重要补充，可为医师鉴别良恶 性卵巢肿瘤提供帮助。

Objective To analyze the clinical value of MRI quantitative diagnosis of ovarian tumors. Methods The medical records of 91 patients with ovarian tumors who admitted to the hospital from June 2015 to June 2018 were selected. All patients were examined by MRI and treated with surgery. According to the pathological results, they were divided into malignant group (n=35, pathologically confirmed as malignant ovarian tumor) and benign group (n=56, pathologically confirmed as benign ovarian tumor). The imaging features, MRI quantitative parameters [capacity transfer constant (Ktrans), rate constant (Kep), extravascular extracellular space-volume fraction (Ve)] and apparent diffusion coefficient (ADC) values of both groups were analyzed. The above indicators were compared between patients with different stages, and the efficiencies of quantitative parameters and ADC in the differential diagnosis of benign and malignant ovarian tumors were analyzed. Results The Ktrans, Kep and Ve in benign group were lower than the control group, and the ADC value was higher than the control group (P<0.05). The tumors in benign group were type I (inflow type) while those in malignant group mainly were type III (outflow type). With the increase of FIGO stage, the Ktrans, Kep and Ve of patients with malignant ovarian tumors increased, and the ADC value decreased (P<0.05). Among the quantitative parameters, the AUC, specificity and the maximum Youden index of Ktrans were the largest in diagnosis of malignant ovarian tumors, followed by ADC, Kep and Ve. The sensitivity of ADC was the highest in diagnosing malignant ovarian tumors. Conclusion MRI quantitative parameters are an important supplement for routine MRI in the diagnosis of ovarian tumors and clinical staging. They help the identification of benign and malignant ovarian tumors.