目的 研究超微血管成像(SMI)及 超声造影(CEUS)在不同厚度颈动脉斑块新 生血管中的临床应用效果。方法 选取92 例颈动脉粥样硬化斑块患者，所有患者均 行颈部动脉多普勒探查确定目标斑块，再 行SMI以及CEUS检查，利用两种检查方式 观察斑块内新生血管情况。结果 斑块厚 度严重程度分级随SMI评分及CEUS评分的 升高而升高，不同SMI评分、CEUS评分患 者斑块厚度严重程度分级比较有统计学意 义(P＜0.05)；SMI评分与CEUS评分一致性 较好(Kappa=0.475，P＜0.05)。结论 SMI 技术和CEUS检测应用于颈动脉斑块内新生 血管的检测，均有较高的诊断价值，SMI 技术无需造影剂辅助，具有无创、价廉的 优点，可作为检测颈动脉斑块新生血管的 首选检查方式。

Objective To study the clinical application effects of superb microvascular imaging (SMI) and contrast-enhanced ultrasound (CEUS) in neovascularization of carotid plaques with different thickness. Methods A total of 92 cases of patients with carotid atherosclerotic plaques were selected and given cervical artery Doppler exploration to determine the target plaque, and then they were given SMI and CEUS. Two methods were used to observe the neovascularization in the plaques. Results The severity grading of plaque thickness was increased with the increase of SMI score and CEUS score, and there were statistically significant differences in the severity grading of plaque thickness in patients with different SMI scores and CEUS scores (P<0.05). SMI score was in good consistency with the CEUS score (Kappa=0.475, P<0.05). Conclusion Both of SMI technique and CEUS detection have high diagnostic value in the detection of neovascularization of carotid plaques. SMI technique does not require contrast agent, and has the advantages of non-invasive and low cost, and it can be used as a preferred detection method for detecting neovascularization of carotid plaques.