目的 探讨MRI在脊柱硬膜外淋 巴瘤与白血病的诊断及鉴别诊断分析。 方法 选择2016年3月-2018年3月我院收 治并确诊的脊柱硬膜外淋巴瘤(15例)和 白血病(10例)患者共计25例，将其病例 资料进行回顾性分析。使用磁共振成像 仪扫描，观察脊柱硬膜外淋巴瘤与白血 病发病部位及MRI表现情况。结果 共25 例患者中23例(92.00%)出现脊柱及其附 件弥漫性病变，且多为脊柱硬膜外淋巴 瘤，其中胸段椎管内硬膜外病变患者最 多。对MRI表现部位进行分析，发现脊 柱硬膜外淋巴瘤多发于椎管及椎管外， 而白血病则多发于椎管内，差异有统计 学意义(P＜0.05)；脊柱硬膜外淋巴瘤 好发于胸椎，而白血病则胸椎、腰骶椎 及骨盆均有发生，差异有统计学意义(P ＜0.05)。对MRI表现情况进行分析，发 现脊柱硬膜外淋巴瘤矢状面T1WI、T2WI病 变节段呈弥漫性斑点状、斑片状出现短 T2信号，且横断面T1WI、T2WI硬膜外软组 织呈新月、半月形等T1和等T2信号，而 白血病均未出现，差异有统计学意义(P ＜0.05)。结论 脊柱硬膜外淋巴瘤与白 血病的MR表现有一定特征，MR对疾病诊 断有一定参考价值。

Objective To investigate MRI diagnosis and differential diagnosis spinal epidural lymphoma and leukemia. Methods The medical records of patients with spinal epidural lymphomas (15 cases) and leukemia (10 cases) who admitted to the hospital from March 2016 to March 2018 were analyzed retrospectively. All cases received MR examination and analyze the location and MRI findings of spinal epidural lymphoma and leukemia. Results Of the 25 patients, 23 (92.00%) had diffuse lesions of the spine and its appendages, and most of them were spinal epidural lymphomas. Patients with thoracic segment and intraspinal epidural lesions were the most. MRI findings showed that spinal epidural lymphomas mostly occurred in the spinal canal and outside spinal canal, while leukemia mainly occurred in the spinal canal (P<0.05). Spinal epidural lymphomas mainly occurred in the thoracic vertebrae, while leukemia mainly occurred in the thoracic vertebrae, lumbosacral vertebrae and pelvis (P<0.05). MRI findings showed diffuse spotted and patchy short T2 signal on sagittal T1WI and T2WI of spinal epidural lymphomas, and semilunar and half-moon-shaped equal T1 and equal T2 signal on cross-sectional T1WI and T2WI of epidural soft tissues. However, such findings were not found in patients with leukemia (P<0.05). Conclusion MRI findings of spinal epidural lymphoma and leukemia are characteristic, which is of certain reference value for diagnosis of the disease.