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双源CT双能量成像在痛风尿酸盐结晶检测中应用价值

作者:刘勇玲 范红燕 赵 庆 慕建成

所属单位:河南省焦作市第二人民医院CT室(河南 焦作 454000)

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摘要

目的 探讨双源CT双能量成像 在痛风尿酸盐结晶检测中应用价值。方 法 回顾性分析30例经临床确诊痛风患 者和12例高尿酸血症患者的双能量CT表 现。结果 共30例痛风患者DECT发现尿酸 盐结晶沉积,其中单关节受累17例,多 关节受累13例,以指(趾)间关节及其周 围软组织最明显;12例高血尿酸患者, DECT检查发现4例有尿酸盐结晶沉积。结 论 双源CT双能量成像技术具有简便、无 创、快捷、灵敏、准确及可重复性强等 优势,可以作为痛风诊断、疗效评估及 痛风高危人群筛查的首选检查方法。

Objective To investigate the application value of dual source dual energy CT in the detection of gout crystals. Methods The dual energy CT findings of 30 patients with gout and 12 patients with hyperuricemia were analyzed retrospectively. Results Uric acid crystal deposition was detected in30 patients with gout, including 17 cases of single joint involvement and 13 cases of multiple joints involvement. The interphalangeal joint and its surrounding soft tissue were the most obvious. There were 4 cases were found uric acid deposit by DECT in 12 patients with hyperuricemia. Conclusion Dual-source dual-energy CT has the advantages of simple, non-invasive, rapid, sensitive, accurate and repeatable. It can be used as the preferred method for diagnosis, evaluation of therapeutic effect and screening of high-risk gout population..

【关键词】双源CT;双能量成像;痛 风;尿酸盐结晶

【中图分类号】R58;R81

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.02.044

前言

痛风是由单钠尿酸盐沉积所致的晶体相关性关节病,与嘌呤代谢 紊乱和(或)尿酸排泄减少所致的高尿酸血症直接相关。双能量CT成像 技术是目前唯一可以对尿酸盐结晶进行伪彩标记的影像检查技术,可 无创、定性、定量检测尿酸盐结晶[1]。通过回顾性分析30例经临床确 诊痛风患者和12例高尿酸血症患者的双能量CT表现,旨在探讨双源CT 双能量成像(Dudl-energy Computed Tomography,DECT)在痛风尿酸盐 结晶检测中的应用价值。