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剖宫产切口妊娠患 者MRI影像特点及 临床结局分析

作者:韦昕芳1 赵华山2 姜 陵1 薛玲玲1 张 瑞1

所属单位:1.河南科技大学第一附属医院新区 医院妇产科 (河南 洛阳 471003) 2.河南科技大学第一附属医院新区 医院影像科 (河南 洛阳 471003)

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摘要

目的 分析剖宫产切口妊娠 (CSP)患者磁共振成像(MRI)影像特点及 临床结局。方法 回顾性收集2015年1 月-2017年6月我院收治的34例CSP患者临 床资料,分析其MRI影像特点,并比较不 同分型CSP的影像特征参数及临床结局。 结果 CSP的MRI影像特点为妊娠物于子宫 前壁疤痕处种植。囊状孕囊13例,MRI 表现为T1WI呈低信号,T2WI呈高信号, 增强扫描显示环形薄壁强化。包块状孕 囊21例,MRI表现为T1WI呈等低信号, T2WI呈混杂信号,增强扫描显示环形厚 壁强化。孕囊着床位置的疤痕最小厚度 为(3.61±1.12)mm,孕囊、疤痕相交处 长度(19.46±9.74)mm,孕囊面积大小为 (643.36±197.65)mm2 。血供丰富20例, 血供缺乏14例。外生型20例,内生型14 例;相比于内生型,外生型具有更小的 疤痕厚度及孕囊面积、更大的孕囊与疤 痕相交处长度(P<0.05),且孕囊周边血 供丰富的比例更高(P<0.05)。相比于内 生型,外生型行子宫动脉化疗栓塞比例 及清宫术出血量更大,β-HCG转阴时间 更长,差异有统计学意义(P<0.05)。结论 CSP的MRI影像表现具有特征性,且外生 型与内生型影像特征参数及临床结局存 在差异,MRI检查对临床治疗有重要指导 意义。

Objective To analyze the magnetic resonance imaging (MRI) image features and clinical outcomes of patients with cesarean scar pregnancy (CSP). Methods The clinical data of 34 patients with CSP who were admitted to the hospital from January 2015 to June2017 were retrospectively analyzed, and their MRI image features were analyzed. The image features and clinical outcomes of different types of CSP were compared. Results The MRI image characteristic of CSP was that the pregnancy matter was planted at the scar of the anterior wall of the uterus. There were 13 cases of cystic gestational sacs. MRI showed low signal on T1WI and high signal on T2WI, and enhanced scan showed circular thin-walled enhancement. There were 21 cases of massive gestational sacs. MRI showed low signal on T1WI and mixed signal on T2WI, and enhanced scan showed ring-shaped thick-wall enhancement. The minimum thickness of scar at implantation site was (3.61±1.12) mm, the length of pregnancy sac and scar intersection was (19.46±9.74) mm, and the size of gestational sac was (643.36±197.65) mm2 . The blood supply was rich in 20 cases and lacking in 14 cases. There were 20 cases of exogenic type and 14 cases of endogenous type. Compared with endophytic type, exogenic type had smaller scar thickness and gestational sac area, larger intersect length of gestational sac and scar (P<0.05), and the proportion of rich peripheral blood supply of gestational sac was relatively higher (P<0.05). Compared with the endogenous type, the proportion of uterine artery chemoembolization for exogenic type and the bleeding volume in uterus curettage were higher/more, and the negative conversion time of β-HCGwas longer(P<0.05). Conclusion The MRI image features of CSP are characteristic, and there are differences between extrinsic and endogenous image features and clinical outcomes. MRI examination is of great guiding significance for clinical treatment.

【关键词】剖宫产切口妊娠;磁共振成 像;诊断;临床结局

【中图分类号】R714.2;R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.05.034

前言

剖宫产切口妊娠(cesarean scar pregnancy,CSP)为剖宫产术后 并发症之一,是指孕囊或胚胎着床于既往剖宫产子宫切口瘢痕处。既 往,CSP是一种相对罕见的异位妊娠,但随着全球剖宫产率逐年增高, 其发生率逐渐增高,成为产科面临的棘手问题[1]。CSP诊治不当可致 大出血、子宫切除等不良后果,甚至危及产妇生命。早期正确诊断是 治疗CSP的关键,详细的诊断信息对临床个体化治疗有着重要指导意 义[2]。本研究回顾性收集2015年1月~2017年6月我院收治的34例CSP患 者临床资料,分析CSP的MRI影像特点及临床结局,以期提高其临床诊 断水平,为实施个体化治疗提供指导,现报告如下。