目的 探究手足口病(HFMD)患儿 并神经系统损害的磁共振成像(MRI)诊断 价值。方法 回顾性分析2014年6月-2017 年6月我院收治的186例HFMD合并神经系 统损害患儿的临床资料，分析其MRI检查 结果。结果 186例患儿中有121例出现MRI 阳性表现，阳性率为65.05%，病灶总数为 287个。病灶多发74例(61.16%)，其中对 称性病灶61例(82.43%)，非对称性病灶13 例(17.57%)。病灶在MRI主要表现为T1WI 稍低信号或低信号，T2WI、T2FLAIR、 DWI稍高信号或高信号，片状、斑点状 影，边缘模糊，无占位效应，部分病灶在 T2FLAIR、DWI序列显示更清楚。MRI不同 序列对病灶检出率比较：T1WI(35.89%) ﹤T2WI(44.95%)﹤T2FLAIR(77.70%)﹤ DWI(86.06%)(P﹤0.05)。结论 MRI对HFMD 合并神经系统损害的诊断价值较高，其中 T2FLAIR、DWI序列对病灶检出率较高，可 作为患儿早期检查的首选序列。

Objective To explore the diagnostic values of magnetic resonance imaging

(MRI) in children with hand-foot-and-mouth disease (HFMD) complicated with

nervous system damage. Methods The clinical data of 186 children with HFMD

complicated with nervous system damage in our hospital from June 2014 to June 2017

were analyzed retrospectively, and the results of MRI examination were analyzed. Results

Among the 186 cases, 121 were MRI positive with the positive rate of 65.05%, and the

total number of lesions was 287. There were 74 cases (61.16%) with multiple lesions, of

which 61 cases (82.43%) were symmetry lesions and 13 cases (17.57%) were asymmetric

lesions. Lesions in MRI showed mainly slightly low signal or low signal in T1WI and

slightly high signal or high signal in T2WI, T2FLAIR and DWI, and there were flaky

and spot-like shadows, fuzzy edge and no mass effect, and some lesions were more clear

in T2FLAIR, DWI sequences. The detection rates of different MRI sequences showed

that T1WI (35.89%)<T2WI (44.95%)<T2FLAIR (77.70%)<DWI (86.06%) (P<0.05).

Conclusion MRI has high diagnostic values for HFMD with nervous system damage, and

T2FLAIR and DWI sequences have high detection rate for lesions and can be used as the

preferred sequences for early detection of children.