简体中文

论著-头颈部

脑淋巴瘤与高级别 胶质瘤磁敏感加权 成像诊断对比研究

作者:谭德力 李大圣 骆祥伟 张 禹

所属单位:中国人民解放军第105医院影像科 (安徽 合肥 230000)

PDF

摘要

目的 探讨脑淋巴瘤与高级别胶 质在磁敏感加权成像(SWI)信号上的差 异,为临床鉴别诊断提供科学依据。方 法 选取我院收治的脑淋巴瘤和高级别胶 质瘤患者为研究对象,采用回顾性调查方 法研究患者临床和影像学资料,分析其常 规MRI及SWI表现并进行半定量评分。结果 脑淋巴瘤患者共有19个病灶,其中血管 评分为0分的病灶有8个,血管评分为1分 的病灶有9个,血管评分为2分的病灶有1 个,血管评分为3分的病灶有1个;高级别 胶质瘤患者共27个病灶,其中血管评分为 2分及3分的病灶分别为5个及22个;经统 计学检验,脑淋巴瘤组与高级别胶质瘤组 血管评分差异显著(P<0.05)。结论 SWI 能够直观显示肿瘤内的磁敏感信号,有助 于脑淋巴瘤和高级别胶质瘤的鉴别诊断, 具有重要的临床价值。

Objective To investigate the difference in signal between cerebral lymphoma and high grade glioma on magnetic susceptibility weighted imaging(SWI), and to provide scientific evidence for clinical differential diagnosis. Methods The patients with cerebral lymphoma and high-grade glioma in our hospital were selected as the research subjects, the clinical and imaging data of patients were analyzed by retrospective study. The routine MRI and SWI findings were analyzed, and semi quantitative scoring was performed. Results There were 19 lesions in patients with cerebral lymphoma, of whom 8 had 0 point in vessel scores, and 9 had 1 points. 1 lesion with 3 points. There were 27 lesions in the patients with high grade glioma, including 5 lesions with blood vessel score of 2, and 22 lesions with a blood vessel score of 3. There was significant difference in vascular score between the brain lymphoma group and the high grade glioma group(P<0.05).Conclusion SWI can directly display magnetic susceptibility signals in tumors, and is helpful for the differential diagnosis of brain lymphoma and high-grade gliomas. It has important clinical value.

【关键词】磁敏感加权成像;脑淋巴瘤; 高级别胶质瘤;鉴别诊断价值

【中图分类号】R739.4;R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.05.005

前言

脑淋巴瘤和高级别胶质瘤均是脑内的恶性肿瘤[1-2],严重威胁患者 的生命安全。脑淋巴瘤和高级别胶质瘤在早期均无显著临床表现,且 MRI特征可以随着免疫状态、组织学类型变化而变化,使诊断具有挑 战性[3]。并且,二者的治疗方式有较大的差异,脑淋巴瘤以放化疗为 主,高级别胶质瘤以手术治疗为主[4]。因此,对于二者的准确鉴别显 得尤为重要。SWI是一种磁共振技术[5],能够显示这两类肿瘤内的磁敏 感信号,逐渐用于临床,但如何识别两者之间的磁信号差异仍需要深 入研究。为探讨这两类肿瘤在SWI上的差异,笔者回顾性分析我院收治 的16例脑淋巴瘤及26例高级别胶质瘤,分析其SWI表现,探讨二者在 SWI上的差异,以期为二者的鉴别诊断提供理论依据。