目的 分析脑灰质异位症患者临 床表现及CT、MRI影像学特征。方法 收集 2013年6月-2016年7月我院收治的56例脑 灰质异位症患者的临床资料，所有患者入 院后均接受CT、MRI平扫及增强扫描，总 结其临床表现及影像学特征。结果 本组 脑灰质异位症男性居多，年龄以18岁以下 青少年为主，症状以癫痫发作就诊居多， 病变均为单发，脑灰质结节位于室管膜 下占41.07%，非室管膜下55.36%，混合型 3.57%；CT平扫脑灰质异位症患者异位灰 质呈相对高密度，与脑皮质密度相同，增 强扫描无强化特点，未见水肿及明显占位 效应，仅巨大脑灰质异位灰质部分见占位 效应；异位灰质MRI T1WI、T2WI序列均呈 等皮质信号，与正常大脑皮质信号一致， 见结节状、团块状、带状或板状信号影， 周围未见水肿，无占位效应，增强扫描未 见强化。结论 脑灰质异位症男性多见， 发病群体以青少年为主，以室鼓膜下型多 见，形态多为结节型，CT及MRI均可较好 显示灰质异位灶，但MRI软组织分辨率更 高。

Objective To analyze the clinical features and imaging findings of CT and MRI of patients with brain gray matter heterotopia. Methods The clinical data of 56 patients with brain gray matter heterotopia treated in the hospital from June 2013 to July 2016 were collected. All patients received plain scan and enhanced scan of CT and MRI. The clinical features and imaging findings were summarized. Results Most of the enrolled patients with brain gray matter heterotopia were male adolescents under the age of 18. Most of the patients were treated because of epilepsy, and lesions were solitary. Brain gray matter nodules located in under the tympanic membrane accounted for 41.07%, nonsubependymal nodules accounted for 55.36%, and mixed type accounted for 3.57%. CT scan found that the brain gray matter of patients with brain gray matter heterotopia showed relatively high density which was the same with cortical density. Enhanced scan showed no enhancement, no edema or obvious mass effect unless huge brain gray matter heterotopia. MRI T1WI and T2WI sequences of heterotopic brain gray matter showed equal cortical signals which were consistent with normal cortical signals. There was nodular, massive, banded or platy signal shadow, and there was no edema around and no space occupying effect. Enhanced scan showed no enhancement. Conclusion Brain gray matter heterotopia is common in male adolescents, the common type is subependymal type, and most lesions are nodular. Both of CT and MRI can better display ectopic foci of gray matter, but the resolution of soft tissue displayed by MRI is relatively higher.