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乙肝肝硬化相关性 小肝癌的影像学诊 断分析

作者:马建平1 马洪德1 刘百舸1 陈鲁豫2

所属单位:1.河南省平顶山市第一人民医院传 染科 (河南 平顶山 467000) 2.河南省平顶山市第一人民医院影 像科 (河南 平顶山 467000)

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摘要

目的 探讨CT对乙肝肝硬化相关 性小肝癌(SHCC)的诊断价值。方法 回顾 性分析我院收治的73例乙肝肝硬化相关 性SHCC临床资料,术前均行肝脏CT平扫 和增强扫描,以病理结果为金标准,分析 CT对乙肝肝硬化相关性SHCC的诊断价值。 结果 73例患者中,CT平扫检出SHCC癌灶 59个(64.13%),CT增强扫描检出SHCC癌灶 85个(92.39%),CT增强扫描检出率显著高 于平扫(P<0.05);其中60例为单发,13例 为多发;癌灶形态为类圆形,直径0.6- 3.0(2.09±0.65)cm;分布位置:肝右叶 54例,肝左叶19例;CT平扫高密度3个, 低密度56个,等密度34个;肝动脉期检 出癌灶84个(91.30%),高密度(明显均匀 强化)63个,边缘强化或中心点状强化17 个,低密度4个,等密度8个;门脉期检 出癌灶66个(71.74%),高密度8个,低密 度58个,等密度26个;延迟期检出癌灶 73个(79.35%),均呈低密度,另19个呈 等密度。各期扫描检出率存在显著差异 (P<0.05)。结论 CT三期增强扫描可显示 乙肝肝硬化相关性SHCC的强化特征,有助 于提高SHCC的检出率。

Objective To explore the diagnostic values of CT for small hepatocellular carcinoma (SHCC) related to hepatitis B cirrhosis. Methods The clinical data of 73 cases of patients with hepatitis B cirrhosis-associated SHCC in our hospital were analyzed retrospectively. And they were given the CT plain scan and enhanced scan for liver preoperatively. The pathological results were taken as the gold standard to analyze the diagnostic values of CT for hepatitis B cirrhosis-associated SHCC. Results Among the 73 patients, 59 (64.13%) cases of SHCC cancer were detected by CT plain scan and 85 (92.39%) cases were detected by CT enhanced scan, and the detection rate of CT enhanced scan was significantly higher than that of plain scan (P<0.05). Among them, 60 cases were single lesions and 13 cases were multiple lesions. The morphology of the lesion was round with the diameter of 0.6-3.0 (2.09±0.65) cm. 54 cases were distributed in right lobe of liver and 19 cases in left lobe of liver. There were 3 high density, 56 low density and 34 equal density by CT plain scan. In the hepatic artery phase, 84 (91.30%) cancer foci were detected, 63 in high density (markedly uniform enhancement), 17 in edge enhancement or central point enhancement, 4 in low density and 8 in equal density. In the portal venous phase, 66 (71.74%) cancer foci were detected , 8 in high density, 58 in low density and 26 in equal density. In the delayed phase, 73 (79.35%) cancer foci were detected with low density, and other 19 in equal density. There were significant differences in the detection rate in the each phase (P<0.05). Conclusion Three-phase CT enhanced scan can show the enhanced features of hepatitis B cirrhosis-associated SHCC and help to improve the detection rate of SHCC.

【关键词】乙肝肝硬化;小肝癌;X线计 算机;断层摄影

【中图分类号】R735.7

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.05.031

前言

我国是慢性乙型肝炎(简称乙肝)、肝硬化高发区,乙肝肝硬化相 关性原发性肝癌也非常常见,且患病者基数众多[1]。肝硬化与肝癌联 系紧密,肝癌是由肝硬化再生结节恶化而成,大部分原发性肝癌患者 伴有肝硬化,而小肝癌(small hepatocellular carcinoma,SHCC)是 指直径≤3cm的原发性肝癌[2]。目前,SHCC的鉴别诊断主要依靠影像学 检查和辅助性血清学检查,影像学检查如CT、MRI,可对癌灶进行定 性、定位的图像分析,在SHCC手术、介入治疗及预后评估中发挥重要 的作用[3]。本研究回顾性分析我院收治的73例乙肝肝硬化相关性SHCC 临床资料,旨在探讨256排CT对乙肝肝硬化相关性SHCC的诊断价值,报 道如下。