论著-头颈部
多层螺旋CT与核磁 共振在原发性肝癌 介入术后病灶残留 及复发中的应用价 值
作者:彭 川 罗 鹰 夏玉梅
所属单位:四川省攀枝花市中西医结合医院放 射科 (四川 攀枝花 617000)
PDF摘要
目的 探讨多层螺旋CT与核磁 共振(Magnetic Resonance Imaging, MRI)在原发性肝癌(primary hepatic carcinoma,PHC)介入术后病灶残留及复 发中的应用价值。方法 选取本院2015 年6月-2017年6月收治的PHC患者60例为 研究对象,共84个病灶,患者均在行经 导管肝动脉化疗栓塞术(transarterial chemoembolization,TACE)后2-6个月 来院复查,采用多层螺旋CT、MRI和数 字减影血管造影(Digital Subtraction Angiography, DSA)检查。以DSA为金标 准,比较多层螺旋CT和MRI检查对术后 病灶残留、复发诊断的准确度、敏感 度、特异度,以及对病灶肿瘤包膜的检 出率。结果 多层螺旋CT病灶残留或复 发诊断准确度、敏感度、特异度分别为 79.76%、72.58%和100.00%,MRI病灶残留 或复发诊断准确度、敏感度、特异度分 别为94.05%、91.94%和100.00%,MRI诊 断的准确度和敏感度显著高于多层螺旋 CT(P<0.05);多层螺旋CT肿瘤包膜检出率 为3.57%,显著低于MRI肿瘤包膜检出率 10.71%(P<0.05)。结论 MRI对于PHC患者 TACE术后疗效诊断准确度高,明显优于多 层螺旋CT诊断。
Objective To explore the application values of multi-slice spiral CT and magnetic resonance imaging (MRI) in the lesion residues and recurrence of primary hepatic carcinoma (PHC) intervention. Methods 60 cases of PHC patients treated in our hospital from June 2015 to June 2017 were selected for the study with a total of 84 lesions, and all the patients were given the review at 2-6 months after the transarterial chemoembolization (TACE). The multi-slice spiral CT, MRI and digital subtraction angiography (DSA) were performed. The accuracy, sensitivity, specificity of the lesion residues and recurrence and the detection rate of the lesion tumor capsule were analyzed by the multi-slice spiral CT and MRI examination taking the DSA as the gold standard. Results The accuracy, sensitivity and specificity of lesion residues and recurrence were 79.76%, 72.58% and 100.00% respectively by the multi-slice spiral CT and were 94.05%, 91.94% 100.00% by MRI, and the accuracy and sensitivity of MRI diagnosis were significantly higher than those by multi-slice spiral CT (P<0.05). The detection rate of the lesion tumor capsule by multi-slice spiral CT was significantly lower than that by MRI (3.57% vs 10.71%) (P<0.05). Conclusion MRI has the high accuracy of efficacy diagnosis for PHC patients after TACE, which is significantly better than the multi-slice spiral CT diagnosis.
【关键词】多层螺旋CT;核磁共振;原发 性肝癌;行经导管肝动脉化疗 栓塞术;病灶残留及复发
【中图分类号】R735.7
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.05.027
前言
原发性肝癌(primary hepatic carcinoma,PHC)是我国中年以上 男性易发的恶性肿瘤之一,发病原因可能与病毒性肝炎、肝硬化、化 学致癌物质以及环境等因素相关。PHC患者一般表现为肝脏进行性肿 大、肝区疼痛、消瘦、乏力、呕吐、腹泻等症状[1-2]。手术根治性切 除是PHC治疗的最有效方法,但因PHC早期无明显临床症状、发病迅 速且易转移,许多患者临床确诊时已失去手术治疗机会[3]。对于无法 进行手术治疗的患者,行经导管肝动脉化疗栓塞术(transarterial chemoembolization,TACE)不仅可对肿瘤进行药物化疗,还可阻断 肿瘤动脉供血,对预后有积极作用,是目前PHC非手术治疗的首选方 法[4]。然而PHC患者TACE术后疗效的客观、准确评价也十分重要,以往 常采用数字减影血管造影(Digital Subtraction Angiography, DSA) 和电子计算机断层扫描(Computed Tomography,CT)技术评价治疗疗 效,随着磁共振成像(Magnetic Resonance Imaging,MRI)技术的发展 和普及,其在TACE术后疗效评估方面也得到广泛应用。本研究旨在比 较多层螺旋CT和MRI对PHC患者TACE术后病灶残留及复发等评估的应用 价值,现报道如下。
中国CT和MRI杂志
第16卷, 第 5 期
2018年05月
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