论著-头颈部
MRI在评估原发性扩 张型心肌病患者心 室功能中的应用
作者:金红瑞 张文博 王可颜 靳亚楠 李舒曼 程敬亮
所属单位:郑州大学第一附属医院磁共振科 (河南 郑州 450000)
PDF摘要
目的 研究核磁共振检查(MRI) 评估原发性扩张型心肌病(IDCM)患者心 室功能中的效果。方法 回顾性分析85 例IDCM患者资料,根据心功能分级标准 分为Ⅰ-Ⅱ级(n=20)、Ⅲ级(n=35)和Ⅳ级 (n=30),分析MRI与二维超声(2DE)评价 心室功能价值。结果 85例IDCM患者均存 在左右心室不同程度扩张,以左侧心室扩 张为主,MRI检查中,36例左心扩大,左 室多呈球形,室壁厚度变薄,49例双侧心 室扩大,心肌运动弥漫性减弱;2DE检查 所有患者均显示全心扩大,56例以左心室 扩大为主,室间隔及左室后壁厚度变薄, 室壁运动弥漫性减弱;随着IDCM患者心功 能分级增高,MRI检查的LVEDV、LVESV逐 渐升高,LVSV、LVEF、LVPER、LVPFP逐渐 降低,不同等级差异显著(P<0.05);2DE 检查的LVESV逐渐升高,LVEF逐渐降低, 不同等级患者间差异显著(P<0.05);; 2DE与MRI检查在室间隔、前壁、后壁厚度 的测量上无显著性差异(P>0.05),在侧壁 与心尖部厚度检查中差异显著(P<0.05)。 结论 2DE与MRI均可有效评估IDCM患者心 室功能,但2DE易低估左心室容积、重复 性差,而MRI则可提供更多左心室功能、 容积等参数,可重复性高,评估心脏功能 和心室壁厚度更加准确,临床应用价值更 高。
Objective To study the effects of magnetic resonance imaging (MRI) on ventricular function in patients with idiopathic dilated cardiomyopathy (IDCM). Methods The data of 85 IDCM patients were retrospectively analyzed. According to the standard of cardiac function, they were divided into grade Ⅰ~Ⅱ (n=20), grade Ⅲ (n=35) and grade Ⅳ (n=30). The values of MRI and two-dimensional echocardiography (2DE) in evaluation of ventricular function were analyzed. Results There were different degrees of left and right ventricle dilation among 85 IDCM patients, mainly in left ventricular dilation. In MRI examination, there were 36 cases of left ventricular enlargement with the mainly spherical left ventricle and the thinner wall thickness, and there were 49 cases of bilateral ventricular enlargement with the diffusely weakened myocardial motion. 2DE examination showed that all patients were with complete heart enlargement, of which 56 cases were mainly left ventricular enlargement with thinner ventricular septum and left ventricular posterior wall thickness and diffusely weakened ventricular wall motion. With the increase of cardiac function grades in IDCM patients, the levels of LVEDV and LVESV by MRI were increased gradually while the levels of LVSV, LVEF, LVPER and LVPFP were gradually decreased, and there was significant difference among different grades (P<0.05). The LVESV level by 2DE was increased gradually while the LVEF level was decreased gradually, and the differences among the different grades of patients were significant (P<0.05). There was no significant difference in the thickness of ventricular septum, anterior wall and posterior wall between 2DE and MRI (P>0.05), but there were significant differences in the thickness of lateral wall and apex of heart(P<0.05). Conclusion Both 2DE and MRI can effectively assess the ventricular function of IDCM patients, but 2DE tends to underestimate left ventricular volume with poor reproducibility whereas MRI provides more parameters of left ventricular function and volume with high reproducibility. And MRI can more accurately assess the cardiac function and ventricular wall thickness, and it has high clinical application values.
【关键词】核磁共振;原发性扩张型心 肌;心室功能
【中图分类号】R445.2;R542.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.05.020
前言
原发性扩张型心肌病(IDCM)进展缓慢,早期临床症状不明显,病 程进展至后期预后极差,及早确诊对于患者治疗和预后有十分重要的 意义[1]。二维超声(2DE)是心脏疾病诊断的常见手段,虽在IDCM的诊断 中具有一定的价值,但其诊断受操作者影响较大,重复性低[2]。核磁 共振(MRI)不受心腔情况的影响,具有多参数、对序列、高分辨率、 重复性高等优点,可准确测量心室容量,评估心脏功能,为IDCM病情 提供更为全面的评估数据,已成为IDCM心功能评估的另一影像学手 段[3]。但MRI检查费用较高,且临床普及率较2DE低,为比较两种检查 方法在评估IDCM患者心室功能中的应用价值,我院开展如下研究。
中国CT和MRI杂志
第16卷, 第 5 期
2018年05月
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