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DSA与颅脑CT在脑梗 塞患者诊治中的应 用*

作者:董志辉 尹 峰 莫哲恒 李发中 雷其良

所属单位:河南省洛阳市中心医院CT室影像诊 断 (河南 洛阳 450000)

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摘要

目的 分析数字减影血管造影 (DSA)与颅脑CT在脑梗塞患者诊治中的应 用价值。方法 选取2016年1月-2017年1月 我院收治的80例脑梗塞病例纳入研究, 依据检查方法差异分为A组(n=40)与B组 (n=40),A组患者行DSA检查,B组行颅脑 CT检查,并按照检查结果给予治疗,比较 2组血管图像质量、病灶检出情况、短期 神经功能缺损(NIHSS)评分变化,并观察 DSA在脑梗塞患者治疗中的应用效果。结 果 2组颅内血管图像质量分级、基底动脉 与后交通动脉图像评分比较差异无统计学 意义(P>0.05);A组颈内动脉岩段、颈内 动脉虹吸段图像评分、治疗24h后NIHSS评 分明显低于B组(P<0.05);2组>2mm梗死 病灶检出率比较无显著差异(P>0.05); A组<2mm梗死病灶检出率25.00%,明显 高于B组7.50%(P<0.05);A组40例患者 中,DSA提示右侧颈内动脉终末段闭塞 12例(30%),取栓后闭塞再通,无残余 狭窄;右额颞叶、基底节区脑梗塞14例 (35%);右侧大脑中动脉M1段闭塞9例 (22.50%),脉溶栓后再通;左侧椎动脉 小脑后下动脉以远闭塞3例(7.50%),溶 栓后小脑后下动脉显影较前好转。结论 相对于颅脑CT,DSA血管成像质量较好, 可以更准确检出脑梗塞患者病灶情况,为 其临床治疗提供有效参考。

Objective To analyze the application values of digital subtraction angiography (DSA) and brain CT in the diagnosis and treatment of patients with cerebral infarction. Methods 80 cases of patients with cerebral infarction treated in our hospital from January 2016 to January 2017 were selected for the study and divided into the A group (n=40) and the B group (n=40) according to different examination methods. The A group was given the DSA, and the B group was given the craniocerebral CT, and they were treated according to the test results. The vascular image quality, lesion detection and short-term neurological deficit (NIHSS) score were compared between the two groups, and the application effect of DSA in the treatment of cerebral infarction was observed. Results There was no significant difference between the two groups in intracranial vascular image quality grade and the scores of basilar artery and posterior communicating artery image (P>0.05). The scores of internal carotid artery petrous segment and internal carotid artery siphon segment, and NIHSS score after 24h of treatment in the A group were significantly lower than those in the B group (P<0.05). There was no significant difference in the detection rate of infarction > 2mm between the two groups (P>0.05). The detection rate of infarction < 2mm in the A group was significantly higher than that in the B group (25% vs 7.50%) (P<0.05). Among the 40 patients ib the A group, there were 12 cases (30%) with end occlusion of right internal carotid artery by the DSA, and they were recanalized after thrombectomy and there was no residual stenosis. And there were 14 cases (35%) with right frontotemporal and basal ganglia cerebral infarction. And there were 9 cases (22.50%) with artery M1 segment occlusion in right cerebra and recanalized after thrombolytic therapy. And there were 3 cases (7.50%) with posterior inferior or distal artery occlusion of the left vertebral artery cerebellum, and the cerebellum posterior inferior artery was developed well after thrombolysis. Conclusion Compared with brain CT, DSA has better angiography quality, and can have more accurate lesions detection of patients with cerebral infarction, and it can provide an effective reference for clinical treatment.

【关键词】数字减影血管造影;颅脑CT; 脑梗塞;诊治

【中图分类号】R651.1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.05.002

前言

脑梗塞亦有缺血性脑卒中之称,致病原因通常是动脉粥样硬化。 有调查发现,在我国人民生活水平不断提升及人口老龄化趋势日益 明显的背景下,脑血管疾病临床发病率正呈现逐年升高趋势,其中 70%~80%为脑梗塞,并且30%发病原因是颈动脉狭窄[1-2]。有文献指 出,65岁以上人群出现颈动脉狭窄性病的机率超过50%,因而早期准确 检查病变并给予有效治疗具有重要意义[3]。数字减影血管造影(DSA)、 磁共振血管造影(MRA)及颅脑CT等均为脑梗塞常用检查方式,均可指导 患者的临床治疗。本文以80例脑梗塞病例作为研究对象,探讨DSA与颅 脑CT在脑梗塞患者诊治中的应用效果,现汇报如下。