目的 观察磁共振(MRI)联合多层 螺旋CT对于肝性脑病(HE)患者诊断准确率 的影响。方法 选取2014年10月-2016年12 月我院收治的75例HE患者作为研究组，纳 入同期73例健康体检者作为对照组，均行 MRI、多层螺旋CT检查，统计研究组MRI、 多层螺旋CT临床表现，并对比MRI、多层 螺旋CT单项诊断及联合诊断灵敏度、特 异度及准确率。结果 两者联合诊断灵敏 度、特异度及准确度(98.66%、97.26%、 97.97%)均高于MRI(82.66%、82.19%、 82.43%)、多层螺旋CT(80.00%、83.56%、 81.76%)单项检测，差异有统计学意义(P ＜0.05)。75例HE患者，67例慢性HE患 者，中脑腹侧高信号16例，T1W1序列呈现 双侧基底节苍白球区高信号55例，垂体前 叶高信号22例，44例多层螺旋CT及MRI出 现脑萎缩；8例急性HE患者，5例中脑腹侧 及双侧基底节苍白球区高信号，4例多层 螺旋CT及MRI出现弥散性脑水肿变化。结 论 MRI联合多层螺旋CT可提高HE患者诊断 灵敏度、特异度、准确率，为HE患者诊治 及预后提供重要指导依据。

Objective To observe the effect of magnetic resonance (MRI) combined with multi-slice spiral CT on the diagnostic accuracy of hepatic encephalopathy (HE). Methods A total of 75 cases of HE patients treated in our hospital from October 2014 to December 2016 were selected as the study group, and 73 healthy persons were taken as the control group in the same period, both groups underwent MRI, multi-slice spiral CT examination, and the clinical manifestations of the study group were analyzed statistically, and compared the sensitivity, specificity and accuracy of MRI and multi - slice spiral CT. Results The sensitivity, specificity and accuracy of combined diagnosis (98.66%, 97.26%, 97.97%) were higher than those of MRI (82.66%, 82.19%, 82.43%), multi-slice spiral CT (80.00%, 83.56%, 81.76%) single diagnosis, the difference was statistically significant (P<0.05). 75 HE patients, 67 patients with chronic HE, midbrain ventral high signal of 16 cases, T1W1 sequence showed 55 cases of high signal of bilateral basal ganglia globus pallidus, pituitary anterior high signal of 22 cases, 44 cases of multi-slice spiral CT and MRI showed brain atrophy; 8 cases of acute HE patients, 5 cases of ventral ventral and bilateral basal ganglia globus pallidus high signal, 4 cases of multi-slice spiral CT and MRI showed diffuse brain edema. Conclusion MRI combined with multi-slice spiral CT can improve the diagnostic sensitivity, specificity and accuracy in the diagnosis of HE, and provide important guidance for diagnosis and treatment of HE patients.