简体中文

论著-头颈部

轻型脑损伤患者磁敏感加权成像评估价值及其与GCS评分的相关性分析

作者:罗荣芳 何建平

所属单位:陕西省宝鸡市人民医院影像科(陕西 宝鸡 721000)

PDF

摘要

目的 探讨轻型颅脑损伤(mild traumatic brain injury, MTBI)患者磁 敏感加权成像(susceptibility weighted imaging, SWI)评估价值及SWI出血灶面 积、数目与GCS评分的相关性。方法 回 顾性分析2012年6月-2014年8月于我院就 诊的98例MTBI患者临床资料,对比其常规 MRI及SWI对MTBI出血灶检出结果差异; 将SWI下出血灶的面积、数目与临床格拉 斯哥昏迷评分(Glasgow Coma Scale, GCS)评分变化进行Spearman相关性分析, 记录分析结果。结果 ①SWI检出76例 (77.6%)出血灶阳性,显著高于常规MRI 的55例(56.1%),差异具有统计学意义 (P<0.05);常规MRI检出251个出血灶,中 位数为(4.5±1.6),SWI检出389个出血 灶,中位数为(6.8±1.7),组间对比差异 具有统计学意义(P<0.05);②SWI下出血 灶的面积、数目与临床GCS评分均呈负相 关性(P<0.05)。结论 SWI对提高MTBI患者 出血灶检出率,帮助医师准确掌握出血灶 数目、面积及分布位置以提高后续治疗工 作的针对性、有效性等具有积极影响,值 得临床推广;SWI出血灶面积和数目均与 GCS评分呈负相关性,需引起临床重视。

Objective To investigate the evaluation value of magnetic susceptibility weighted imaging (SWI)in patients with mild traumatic brain injury (MTBI) and the correlation between the area and number of SWI hemorrhagic lesions and GCS. Methods The clinical data of 98 patients with MTBI who were treated in the hospital during June 2012 to August 2014 were retrospectively analyzed. The detection results of conventional magnetic resonance imaging (MRI) and SWI in patients with MTBI were compared. The changes of area and number of SWI hemorrhagic lesions and clinical Glasgow coma score (GCS) were analyzed by Spearman correlation analysis and the results were recorded and analyzed. Results ①There were 76 cases (77.6%)with positive hemorrhagic lesions detected by SWI, significantly more than 55 cases (56.1%) detected by conventional MRI (P<0.05). There were 251 hemorrhagic lesions detected by conventional MRI and the median was (4.5±1.6) while there were 389 hemorrhagic lesions detected by SWI and the median was (6.8±1.7) (P<0.05). ②The area and number of SWI hemorrhagic lesions and clinical GCS were negatively correlated (P<0.05). Conclusion SWI has positive impact on improving the detection rate of hemorrhagic lesions in patients with MTBI and helping doctors accurately control the number, area and distribution of hemorrhagic lesions to improve the pertinence and effectiveness, etc. of follow-up treatment. It is worthy of clinical promotion. The area and the number of SWI hemorrhagic lesions are negatively correlated with GCS, which needs clinical attention.

【关键词】轻型脑损伤;磁敏感加权成 像;GCS评分;相关性

【中图分类号】R445.2;R651.1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.02.005

前言

相关研究表明,轻型脑损伤(MTBI)作为颅脑损伤临床最常见的类 型之一,占总患病群体的6成以上[1],积极有效的早期治疗干预是促 进患者病情转归、提高脑神经修复再生功能、改善患者预后水平的关 键。以往临床诊断MTBI多采用头颅CT平扫联合伤后临床症状表现评估 病情发展情况、预测患者预后水平,缺乏清晰直观的影像学基础,对 微小出血病灶的检出率较低,于患者后续治疗工作的顺利开展不利。 磁敏感加权成像(SWI)作为一种新型影像检查技术,利用不同组织磁 敏感性差异成像[2],对局部磁场变化敏感,能帮助医师获得更清晰的 影像学图像,以准确评估病灶同周围组织解剖关系[3],为治疗方案的 拟定提供条件。本次研究为探讨MTBI患者SWI评估价值及SWI出血灶面 积、数目与GCS评分的相关性,回顾性分析98例MTBI患者临床资料,现 报告如下。