目的 探讨CT灌注参数预测中晚 期宫颈癌鳞癌同步放化疗疗效的价值。方 法 对44例进行为期1年的随访，按照实体 肿瘤的RECIST标准将其分为有效组与无效 组。对各组的灌注参数进行比较，并采用 ROC曲线分析来评价灌注参数预测中晚期 宫颈癌同步放化疗疗效的价值。结果 1、 BV、PMB在两组间差异有统计学意义(t= 3.667,P=0.001;t=3.047,P=0.004)，并且 有效组的BV值、PMB值较无效组高；BF、 MTT、TTP在两组间没有统计学意义。2、 经ROC曲线分析，BV的曲线下面积较PMB 曲线下面积大，所以BV的评价效能较PMB 高。结论 CT灌注成像在中晚期宫颈鳞癌 同步放化疗疗效评价方面有预测价值。

Objective To evaluate the value that CT perfusion parameters to predict the response of synchronous radiochemotherapy for middle-advanced cervical squamous cancer. Methods 44 patients with cervical squamous cancer later than stage ⅡB were included in this study.They were followed up for 1 year. According to the RECIST, patients were divided into the responders group and non-responders group. Perfusion parameters of the two groups were compared. The perfusion parameters that may be effective were analysed by using ROC curve. Results 1.There were significant difference between two groups in BV and PMB. The BV and PMB in patients who received effective response were greater than patients in other groups. There were no significant difference in BF and MTT and TTP between two groups. 2.Analysed by ROC curve, the area under curve of BV were bigger than that of PMB. It counld conclude the diagnostic potency of BV higher than that of PMB. Conclusion CT perfusion could predict the response of synchronous radiochemotherapy for middle-advanced cervical squamous cancer.