目的 探讨超声及CT在鉴别诊断 甲状腺良恶性结节中的临床应用价值。 方法 选取120例(138个结节)甲状腺结 节患者为研究对象,均接受超声及CT检 查，以病理检测结果为“金标准”，评 估CT、超声及CT联合超声检查在鉴别诊 断甲状腺良恶性结节中的准确性、特异 性、敏感性差异。结果 120例甲状腺结 节患者确诊为良性者89例(74.2%)、恶性 者31例(25.8%)；CT联合超声检查正确 诊断恶性结节27例，良性结节85例，诊 断准确性为93.3%、特异性为95.5%、敏 感性为87.1%,均显著高于单纯CT检查的 80.3%、82.0%和77.4%及单纯超声检查的 83.3%、86.5%和74.2%，差异具有统计学 意义(P＜0.05)。结论 CT联合超声检查 可有效提升甲状腺良恶性结节鉴别诊断 准确性，患者耐受程度高，对降低误诊 及漏诊风险、提高诊疗效率等具有积极 意义。

Objective To investigate the clinical application value of ultrasound and CT in differential diagnosis of benign and malignant thyroid nodules. Methods 120 patients (138 nodules) with thyroid nodules were selected as study subjects and received ultrasound and CT examination. With the results of pathological examination as the golden standard, the differences inaccuracy, specificity and sensitivity between CT, ultrasound and CT combined with ultrasound in the differential diagnosis of benign and malignant thyroid nodules were evaluated. Results Among the 120 patients with thyroid nodules, there were 89 cases (74.2%) with benign nodules and 31 cases (25.8%) with malignant ones. There were 27 cases of malignant nodules and 85 cases of benign nodules correctly diagnosed by CT combined with ultrasound, and the diagnostic accuracy, specificity and sensitivity were 93.3% , 95.5% and 87.1%, respectively which were significantly higher than those of simple CT examination (80.3%, 82.0%, 77.4%) and simple ultrasound (83.3%, 86.5%, 74.2%) (P<0.05). Conclusion CT combined with ultrasound examination can effectively improve the accuracy of differential diagnosis of benign and malignant thyroid nodules. The tolerance of patients is high, which is of positive significance in reducing the risk of misdiagnosis and missed diagnosis and improving the efficiency of diagnosis.