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多层螺旋CT血管造影在诊断颅内脑动脉瘤中的临床价值研究

作者:杨秋云 石安斌 翟建春 方文亮 吴继雄 张良金

所属单位:中信惠州医院医学影像中心(广东 惠州 516006)

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摘要

目的 探讨多层螺旋CT血管造影 (multi-slice spiral CT angiography, MSCTA)对颅内脑动脉瘤的临床诊断价 值。方法 以我院2012年2月-2015年8月 经手术或数字减影血管造影 ( d i g i t a l subtraction angiography, DSA)证实的 40例颅内脑动脉瘤患者为研究对象,所 有患者均接受MSCTA检查,观察其表现 (瘤体部位、形态、大小等),同时与DSA 结果比较。结果 MSCTA检出脑动脉瘤38 例(95.0%),DSA检出39例(97.5%),两 组诊断敏感度比较差异无统计学意义(P >0.05)。MSCTA检查脑动脉瘤最大径、 瘤颈最大径分别为(9.98±2.54)mm、 (4.29±1.45)mm,与DSA的(10.07±2.30) mm、(4.32±1.32)mm比较差异无统计学 意义(P>0.05)。MSCTA与DSA对颅内动脉 瘤位置分布诊断结果比较差异无统计学 意义(P>0.05)。结论 MSCTA诊断颅内脑 动脉瘤敏感度较高,与DSA类似,无创且 操作简单,值得临床推广。

Objective To study the clinical value of multi-slice spiral CT angiography (MSCTA) in the diagnosis of intracranial aneurysms. Methods 40 patients with intracranial aneurysms which were confirmed by operation or digital subtraction angiography (DSA) during February 2012 to August 2015 were selected as the research objects. All patients underwent MSCTA examination and their performances (the posotion, form and size, etc. were observed and compared with the results of DSA. Results MSCTA detected cerebral aneurysm in 38 cases (95.0%) and DSA detected 39 cases (97.5%). There was no statistically significant differences in the comparison of diagnostic sensitivity between the two groups (χ2 =0.346, P>0.05). The maximum diameters of cerebral aneurysm and aneurysmal neck detected by MSCTA were (9.98±2.54) mm and (4.29±1.45) mm. Compared with (10.07±2.30) mm and (4.32±1.32) mm detected by DSA, the difference was statistically significant (P>0.05). There was no statistically significant differences in the diagnostic results of the location of intracranial aneurysms diagnosed by MSCTA and DSA (P>0.05). Conclusion The sensitivity of MSCTA in the diagnosis of intracranial aneurysms is highly. It is similar to DSA and is non-invasive and easy to operate, which is worthy of clinical promotion.

【关键词】多层螺旋CT血管造影;颅内 脑动脉瘤;造影表现

【中图分类号】R445.3; R743.4

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.02.011

前言

颅内动脉瘤发病机制尚不明确,好发于40~66岁人群,以先天性 动脉瘤为主[1]。据统计,颅内脑动脉瘤破裂后易引发自发性蛛网膜下 腔出血(subarachnoid haemorrhage,SAH),一旦破裂出血患者病死率 较高,至少占40%[2]。为此早期诊断出颅内脑动脉瘤,及时有效治疗预 防SAH发生十分必要。数字减影血管造影(DSA)作为颅内脑动脉瘤诊断 的“金标准”,诊断准确率较高,但它属于有创操作,加上其检查价 格高,易引发血管痉挛等相关并发症,为此临床应用受限。近年来多 层螺旋CT血管造影(MSCTA)在颅内脑动脉瘤诊断中应用越来越多,具有 无创、操作简单、经济实惠等特点,且有研究表明其诊断敏感度与DSA 类似[3]。基于此,本研究回顾性分析我院2012年2月~2015年8月40例 颅内脑动脉瘤患者MSCTA影像资料,报告如下。